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Method for manufacturing rapid blood sugar test paper

A technology for testing test strips and production methods, which is applied in the field of biosensing, and can solve the problems of complex production process, expensive materials and unfavorable industrial scale production of products, so as to optimize the production process, facilitate post-processing and packaging, and reduce production equipment Effect

Inactive Publication Date: 2008-11-12
胡军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods all use the screen printing technology of multi-layer conductive coating, and also need to use biological element spotting equipment to apply the biological enzyme solution to the surface of the electrode, which complicates the manufacturing process, and also uses conductive silver ink, and the material price Expensive is not conducive to the industrial scale production of products

Method used

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  • Method for manufacturing rapid blood sugar test paper

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: Polyphenylene (PP) synthetic paper, cut into 300X300 centimeter substrate in advance for later use.

[0019] (1) 1 gram of silk-screen conductive carbon ink (Acheson 423SS) was mechanically stirred for 30 minutes, mixed well and set aside.

[0020] (2) Fix the 300-mesh metal or nylon polyester wire mesh on a square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use.

[0021] (3) Place the computer-drawn negatives of the working electrode and the reference electrode on the photosensitive adhesive, and expose them to a 20-watt ultraviolet lamp for 15 minutes. Rinse off the unhardened photosensitive adhesive covered by the electrode negative with a high-pressure water gun. After drying, a screen printing template is formed.

[0022] (4) Install the screen printing template with the working electrode and reference electrode graphics on the automatic screen printing machine for standby.

[0023] (5) Glucose oxidase ...

Embodiment 2

[0026] Embodiment 2: polyester (PET) sheet material, cut into 300 * 300 centimeter substrates in advance for later use.

[0027] (1) Mechanically stir and mix the silk screen conductive carbon ink for later use.

[0028] (2) Fix the 300-mesh metal or nylon polyester wire mesh on a square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use.

[0029] (3) Place the computer-drawn negatives of the working electrode and the reference electrode on the photosensitive adhesive, and expose them to light for 25 minutes under a 20-watt ultraviolet lamp. Rinse off the unhardened photosensitive adhesive covered by the electrode negative with a high-pressure water gun. After drying, a screen printing template is formed.

[0030] (4) Install the screen printing template with the working electrode and reference electrode graphics on the automatic screen printing machine for standby.

[0031] (5) Glucose dehydrogenase with an activity of 350 interna...

Embodiment 3

[0033] Embodiment 3: Polyphenol ester (PP) boards, which are pre-cut into 300×300 cm substrates for later use.

[0034] (1) Mechanically mix the silk screen conductive carbon ink for standby;

[0035] (2) Fix the 300-mesh metal or nylon polyester material screen on the square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use;

[0036] (3) Place the working electrode and the reference electrode negative film drawn by the computer on the photosensitive glue, expose to light for 30 minutes under a 40-watt ultraviolet lamp, rinse off the unhardened photosensitive glue covered by the electrode negative film with a high-pressure water gun, and form a silk screen template after drying;

[0037] (4) Install the screen printing template with working electrode and reference electrode graphics on the automatic screen printing machine for standby;

[0038] (5) Glucokinase with an activity of 120 international units was added to 120 millimoles p...

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Abstract

The invention discloses a matching test paper for a glucose tester and a preparation method thereof, which pertain to the technical field of bio-sensor. The substrate of the test paper is printed with a working electrode, a reference electrode and an electrical circuit; one end of the substrate is printed with a conducting wire connected with a read-out instrument; the working electrode and the reference electrode are carbon coatings which are printed on the substrate at once and printed with biological enzyme, a medium and an adhesive. The method adopts bio-sensor and electrochemical principle, produces the test paper by screen printing which is not restricted to a conductive circuit as well as prints relatively sensitive bio-components directly on an electrode holder; screen printing area is fully controlled by a screen printing machine. The encapsulation of the test paper adopts siphon encapsulation which limits reaction space. Once the test paper of the invention contacts human blood, a limited quantity of blood is sucked into a reaction tank and accurate results can be obtained conveniently and visually from a corresponding matching testing instrument. The glucose test paper has the advantages of simple production method, high accuracy and low cost and is convenient for later process and encapsulation and good for scale production.

Description

technical field [0001] The invention relates to a method for manufacturing quick blood sugar testing test paper, in particular to a method for manufacturing a test paper matched with a blood sugar tester, belonging to the technical field of biosensing. Background technique [0002] According to statistics, the number of diabetic patients in my country has exceeded 45 million, and the number of patients with diabetes is increasing at a rate of 3,000 patients every year. At present, one of the effective means to control the development of diabetes is to implement blood sugar testing every day, so as to strictly control the patient's diet and medication, and maintain the stability of the patient's blood sugar index. The supporting test strips of some blood glucose meters that appear in the domestic market are produced using complex technology. After the basic electrode screen printing is completed, this production process also needs to implement sample processing of biological ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/66G01N33/52C12Q1/26G01N27/327
Inventor 胡军
Owner 胡军
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