External-used burn and scald treating medicine and its preparation

Abstract

The invention relates to a medicine for externally treating burn and scald, which is an ointment prepared from slough tissue of cultured second generation giant salamanders and subsequent generations thereof during growth period, radix glycyrrhizae, borneol, sinkiang arnebia root and sanguisorba officinalis. The inventive ointment is prepared from the radix glycyrrhizae extract, sinkiang arnebia root extract, sanguisorba officinalis extract and nanometer powder of giant salamander slough tissue that are obtained by modern biotechnology. The preparation method og the medicine comprises the steps of mixing according to a certain proportion, adding borneol and matrix that is made of Vaseline, vegetable oil, beeswax and anhydrous lanolin, homogenizing, and making into the ointment. The inventive medicine has the advantages of good therapeutic effect, quick action, good analgesic effect, short treatment course, no scar left, and no any toxic and side effects. Burn and scald rat model experiments prove that the inventive medicine shortens the healing time of the superficial second degree, the deep second degree and the third degree burns, there is no scar left on wound surface after healing for the superficial second degree and the deep second degree burns, and there is less scar left on wound surface after healing the third degree burn, with no need of skin grafting. The inventive medicine has better therapeutic effect than the prior medicines for treating burn and scald, and has very wide application prospect.

Description

technical field [0001] The invention belongs to the field of pharmacy, and relates to a medicine for treating burns and a preparation method thereof. The medicine is prepared from animal and plant tissues as raw materials. Background technique [0002] Burns and scalds with different areas and depths caused by various reasons are common diseases that seriously endanger human health and appearance. Burns refer to the direct burning of flames caused by organic substances, chemical substances, power sources, and radiation on human skin, limbs, and internal organs. The degree of harm to the human body is relatively large, and treatment and treatment methods are relatively difficult; scalds refer to liquids that are higher than the body temperature Burns to the surface and deep layers of human skin by solid, gaseous substances, such as water, oil, chemical agents, acids, alkalis, iron, aluminum, copper, bricks, stones, asphalt, steam, etc. scald. Burns and scalds mainly occur ...

AI Technical Summary

Problems solved by technology

[0004] At present, there are many kinds of medicines for treating burns and scalds, mainly containing 2 classes: the first class is chemically synthesized medicines, such as silver sulfadiazine, etc. These medicines have certain curative effects for treating burns and scalds, but there are many problems and deficiencies: 1. The first is that the elimination of putrefaction skin and bad tissue is slow, and the probability of wound infection increases; the second is that the scabs are slow, which increases water loss and infection; the third is that the patient causes pain when using the drug; the fourth is that the treatment cost is high

The second category is traditional Chinese medicine formula medicines, such as Jingwanhong, etc. These medicines have certain curative effects on the treatment of burns and scalds, but there are also some problems and deficiencies: First, the raw materials of medicines are seldom pretreated, and only through simple crushing It is obtained by mixing, which makes it difficult for drug molecules to be absorbed through the skin, and the bioavailability is relatively low, which leads to slow recovery of patients; second, the number of medications is relatively large, and the dosage is large; third, the price is relatively expensive, which makes it unbearable for ordinary patients