Iron supplementary liposome iron and method of preparing the same
A technology for liposomes and iron supplements, applied in the field of biological sciences, can solve the problem of not finding iron supplements liposome iron, etc., and achieve the effects of reducing drug dosage, improving absorption efficiency and easy operation.
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[0030] The following examples are used to illustrate the present invention.
[0031] The composition of iron supplement liposomal iron:
[0032] The mass ratio of heme iron and / or inorganic iron: cholesterol: lecithin is (0.1~200): (1~10): (10~100)
[0033] Preparation:
[0034]Weigh an appropriate amount of cholesterol and lecithin, the mass ratio of the two is (1-10): (10-100), add a certain amount of organic solvent ethanol, and after it is completely dissolved, place it in a 250ml ground-mouth pear-shaped flask. Then put the pear-shaped flask in a constant temperature water bath of 25~38℃, and use a rotary evaporator to volatilize the organic solvent under the conditions of rotation speed 80~140r / min and reduced pressure (the pressure is kept at 0.08~0.1MPa) to make phospholipids and other films form The material forms a uniform lipid film on the wall of the flask, and then fills the flask with N 2 120~200min to completely remove the solvent; meanwhile, weigh the heme iron acc...
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