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Dropping pills for treating sudden deafness and method for preparing the same

A technology for sudden deafness and dripping pills, which is applied in the directions of medical preparations without active ingredients, medical preparations containing active ingredients, and pill delivery, etc. It can solve problems such as damage to the middle ear structure, middle ear infection, and side effects. , to achieve the effect of not easy recurrence, definite curative effect, and no toxic side effects

Inactive Publication Date: 2010-05-19
周宣岩 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional systemic application of steroid hormones in clinical treatment of sudden deafness has achieved certain results, but high-dose systemic application can cause obvious toxic side effects, such as infection, ulcer disease, osteoporosis, etc.
Moreover, the main action site of hormones is the inner ear, so many scholars now perform local injection of hormones into the tympanum and have achieved good results. However, as a traumatic treatment, it may damage the structure of the middle ear, causing middle ear infection or middle ear infection. Adhesion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Take astragalus, kudzu root, chuanxiong, Shichangpu, salvia, bupleurum, cohosh, wolfberry, scutellaria, earthworm, codonopsis, peach kernel, safflower, uncaria, add water and boil 1 to 5 times, 0.5 to 2 hours each time , combine the decoction, concentrate appropriate amount, add 1 to 4 times the amount of ethanol, let it stand for 12 to 36 hours to precipitate, take the supernatant, recover the ethanol, concentrate it into a thick paste with a relative density of 1.1 to 1.5 for later use. Put the polyethylene glycol-6000 into a dry container and heat to melt, take the above thick paste and add it to the melted auxiliary material polyethylene glycol-6000, and make the material uniform at 80-95°C to obtain the liquid medicine to be dripped. The condensing agent liquid paraffin is pre-cooled to 10-15°C, and the above liquid medicine is dripped into the condensing agent drop by drop at a rate of about 30 drops / min. Take it out, wipe off the condensing agent, and dry it to ob...

Embodiment 2

[0048] Take astragalus, kudzu root, chuanxiong, Shichangpu, salvia, bupleurum, cohosh, wolfberry, scutellaria, earthworm, codonopsis, peach kernel, safflower, uncaria, add water and boil 2 to 4 times, each time for 0.8 to 1.5 hours , combined decoction, concentrated appropriate amount, added 1.5 to 3 times the amount of ethanol, allowed to stand for 18 to 30 hours to precipitate, took the supernatant, recovered ethanol, concentrated into a thick paste with a relative density of 1.2 to 1.45 for later use. Put Polyethylene Glycol-1000 into a dry container, heat and melt, take the prepared thick paste and add molten Polyethylene Glycol-1000, make the material uniform at 80-95°C, drop into cooled 5-10°C liquid paraffin In the middle, drop to make a drop pill, take it out, wipe off the paraffin, and you get it.

Embodiment 3

[0050] Take astragalus, kudzu root, chuanxiong, Shichangpu, salvia, bupleurum, cohosh, wolfberry, scutellaria, earthworm, codonopsis, peach kernel, safflower, uncaria, add water and boil 1 to 5 times, 0.5 to 2 hours each time , combine the decoctions, concentrate an appropriate amount, add 1 to 4 times the amount of ethanol, let stand for 12 to 36 hours to precipitate, take the supernatant, recycle the ethanol, concentrate to a thick paste with a relative density of 1.3 to 1.4 for later use. Put Polyethylene Glycol-1500 into a dry container, heat and melt, take the prepared thick paste and add molten Polyethylene Glycol-1500, make the material uniform at 80-95°C, drop into the cooled 6-8°C liquid paraffin In the middle, drop to make a drop pill, take it out, wipe off the condensing agent, and then get the drop pill.

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Abstract

The invention belongs to the field of traditional Chinese medicine and process for preparation, which is a dropping pill used for curing sudden deafness. Basic ingredients of the invention are constituted by following medicaments: astragalus root, kudzu root, ligusticum chuanxiong, acorus gramineus soland, salvia miltiorrhizae, bupleurum root, cimicifuga foetida, medlar, scutellaria root, lumbricus, lanceolata, peach kernel, safflower, uncaria and proper amount of auxiliary materials, wherein the auxiliary materials are chosen from carbowax-1000-8000 or the mixture of the compositions. The highly effective and quick-effective function of the invention is particularly suitable for curing sudden deafness, the invention can improve the blood supply of inner ear, advance the functional recovery of hair cells of the inner ear, inhibit self immune response, clear free radicals of body and improve auditory acuity, and the sudden deafness can not easily recur after being cured. The invention is a pure traditional Chinese medicine preparation with no side effect and easy administration, which contains no hormone substance. The invention overcomes the defects and shortcomings of original traditional Chinese medicine preparation. The invention can be made into tablets, granules, capsules, pills, oral liquid, dropping pills and the like, and can be used for curing patients with other typesof sensorineural hearing loss or tinnitus.

Description

Technical field: [0001] The invention relates to a Chinese patent medicine for treating diseases such as sudden deafness and a preparation method thereof, in particular to a dripping pill. Background technique: [0002] Sudden deafness is a kind of sensorineural deafness with complex etiology and not fully clear. one. Current studies speculate that the causes of sudden deafness mainly include the following: inner ear blood supply disorder, viral infection, autoimmune disease, genetic factors, and perilymphatic fistula. Therefore, there is no definite treatment plan for sudden deafness, and the treatment is mainly based on the speculated etiology, which lacks pertinence. Many treatment options based on the etiology have been applied clinically, and have achieved varying degrees of effect. There are mainly steroids, hyperbaric oxygen, neurotrophic agents, energy mixtures, vasodilators, etc. Conventional systemic application of steroid hormones in clinical treatment of sudd...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/888A61K36/815A61K36/74A61K36/73A61K36/71A61K36/539A61K36/488A61K36/481A61K36/344A61K36/286A61K36/236A61K36/233A61K35/64A61K47/34A61P27/16A61J3/06A61K35/62A61K47/10
Inventor 周宣岩陶谦张峰
Owner 周宣岩
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