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Anti-inflammatory Chinese medicinal preparation and its preparation technology

A technology for traditional Chinese medicine and compound preparations, which is applied in the directions of antibacterial drugs, drug combinations, and pharmaceutical formulations, and can solve problems such as the inability of antibiotics to meet clinical needs.

Inactive Publication Date: 2007-12-12
朱志宏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After long-term use of antibiotics, humans have realized the serious consequences of the abuse of antibiotics. Since the 1990s, multi-drug-resistant Gram-negative (G-) bacteria have attracted people's attention. The drug resistance of bacteria has been increasing, and the frequency of drug resistance has gradually As a result, conventional antibiotics cannot meet clinical needs, so the current trend of drug resistance is very serious, and controlling the development of this trend has become a major problem in the field of Western medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh 25g of andrographolide and 60g of Ficus microphylla dry extract respectively, mix well, add appropriate amount of auxiliary materials starch, lactose, sodium carboxymethyl cellulose, add appropriate amount of cross-linked polyvinylpyrrolidone, magnesium stearate, etc., pass Appropriate preparation means, such as mixing, granulating, granulating, and tabletting, are prepared into 1000 tablets.

Embodiment 2

[0019] Take Andrographis paniculata and extract, and take by weighing Ficus microphylla dry extract 75g and be prepared into capsules by the following method:

[0020] A. Extract Andrographis paniculata 2 times with water. Add 8 times the amount of water for the first time, decoct for 3 hours, add 12 times the amount of water for the second time, decoct for 1.5 hours, combine the extracts, filter, and concentrate the filtrate to a concentrate equivalent to 3g of the original medicinal material per gram for use.

[0021] B. Weigh 30g of the concentrated solution obtained in A, dry, pulverize and grind it into powder, mix it with the dry extract of Ficus microphylla, add appropriate amount of auxiliary materials starch, sucrose, magnesium stearate, sodium lauryl sulfate, hydroxypropyl methyl Cellulose, etc., granulated, sized, mixed, dried, filled into gelatin capsules. Prepare 1000 capsules.

Embodiment 3

[0023] Weigh 15g of Ficus lobata dry extract and 40g of andrographolide respectively, add an appropriate amount of auxiliary materials such as micropowder silica gel, methylcellulose, starch, hydroxypropylmethylcellulose, etc. to pulverize, sieve, mix evenly, and pack separately to obtain granules 1000 packs.

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Abstract

The invention relates to a traditional Chinese pharmaceutical composition for treating infectious diseases and process for preparation, wherein the composition is prepared from one of green chiretta and green chiretta active constituent of andrographolide (any one of the derivative containing andrographolide), dried concrete of Ficus microcarpa var.pussilifolia, and one or more medicinal auxiliary materials. The invention also provides a process for preparing the Chinese medicinal anti-infective composition.

Description

field of invention [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating infectious diseases and a production process thereof, in particular to a traditional Chinese medicine Andrographis paniculata or its active ingredient andrographolide (a derivative containing andrographolide) and a small Yerong dry extract is a combination of two main medicines, which is used to treat infectious diseases such as cold and fever, chronic bronchitis, pharyngitis, upper respiratory tract infection, bacillary dysentery, and enteritis. Background technique [0002] With the continuous production of various antibacterial drugs represented by penicillin, bacterial infectious diseases that once made human beings helpless have been effectively controlled, thus antibiotics have become a powerful weapon in human hands against pathogenic bacterial infections. After long-term use of antibiotics, humans have re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P31/04A61P11/04A61P11/00A61P1/12A61P1/00A61K31/365
Inventor 朱志宏
Owner 朱志宏
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