Extracting purified ginsenoside from leaves of Panax quinquefolium and ginseng at the same time and the preparing method thereof

Abstract

The present invention relates to Chinese medicine and its extracting and processing technology, and is especially the effective part extracted from American ginseng leaf and ginseng leaf and its preparation process. The extracted effective part contains six kinds of ginsenoside substances, including ginsenoside Re, ginsenoside Rb1, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rc and ginsenoside Rd. Its preparation process includes water extracting American ginseng leaf and ginseng leaf in the weight ratio of 1 to 0.3, macroporous resin adsorption of the water extract liquid, water eluting to eliminate impurity, further eluting with two kinds of elutents, collecting the eluted liquid, and refining the total solid matter to reach purity up to 63.45 %. The extracted effective part has less side effects, and may be used widely in compound medicine preparation and functional food and for separating ginsenoside substance.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine and its extraction and processing, in particular to jointly extracting, separating and purifying effective parts of ginsenoside from American ginseng leaves and ginseng leaves and a preparation method thereof. The active part is ginsenoside Rg 1 Six ginsenoside monomers contained in the following components: ginsenoside Re, ginsenoside Rb 1 , Ginsenoside Rb 2 , Ginsenoside Rb 3 , Ginsenoside Rc, Ginsenoside Rd. Background technique [0002] At present, various scholars extract ginsenoside diol group, triol group, oleanolic acid and pseudo-ginsenoside F from ginseng and American ginseng. 11 , Separation and transformation of ginsenoside monomers, etc. [0003] As far as the current technical research status is concerned, in the study on the separation of ginsenosides and effective parts, there is a lack of innovation in the design principles, index determination, basis and significa...

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Problems solved by technology

Rg 1 The effects of the above components are very unsuitable drugs for patients with rapid heart disease. Long-term use can cause side effects such as epistaxis, irritability, accelerated heart rate, and increased blood pressure. This is the adverse reaction of current clinical application of ginsenoside preparations. There are certain restrictions on the number of people taking

So how to effectively extract, isolate and purify ginsenosides including Rg 1 The extracts of the following components are the subject of research, but have not been reported after searching