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Traditional Chinese medicine compound preparation for treating chronic cholecystitis

A technology for chronic cholecystitis and compound preparations, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., and can solve problems such as liver and kidney toxicity, side effects, poor efficacy, and no treatment methods.

Inactive Publication Date: 2007-08-01
孙蓉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine has no effective treatment method for chronic cholecystitis except operation, and the operation method has not been accepted by most patients. In addition to poor curative effect, western medicine also has diarrhea and liver and kidney toxicity side effects. The majority of patients bring great pain and burden

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] 400g green skin, 400g turmeric, 480g Cyperus cyperi, 240g white mustard seed, 600g salvia miltiorrhiza, 600g astragalus, 60g weeping grass. Grind green bark into the coarsest powder, add 8 times the amount of water to soak for 4 hours, extract the volatile oil by distillation for 6 hours, concentrate the distilled aqueous solution, and reserve; Ethanol reflux extraction twice, each time for 1.5 hours; combined extracts, filtered, the filtrate was decompressed to recover ethanol, dried, crushed through an 80-mesh sieve, and set aside. Add 10 times the amount of water to soak turmeric and Cyperus cyperi for 2 hours, extract the volatile oil by distillation for 5 hours, extract the dregs with 8 times the amount of water for 1 hour, collect the extract, concentrate, and set aside. The volatile oil and the green bark volatile oil are mixed with 6 times the amount of β-cyclodextrin, and clathrated at 50°C for 2 hours. Salvia miltiorrhiza and Astragalus plus 8 times the amoun...

Embodiment 2

[0096] Preparation of granules:

[0097] Prescription: Qingpi 400g, Curcuma 400g, Cyperus Cyperi 480g, White Mustard Seed 240g, Salvia miltiorrhiza 600g, Astragalus 600g, Weeping grass 600g.

[0098] The extraction process was as described above. The extract obtained by extracting and concentrating is placed in an oven and blast-dried, crushed and passed through an 80-mesh sieve to obtain a dry powder. Add dextrin with 2 times the weight of dry powder, 2% stevioside, and both dextrin and stevioside are passed through a 80-mesh sieve. Moisten the soft material with 70% ethanol, pass through a 14-mesh sieve to granulate, dry the wet granules at 60°C, granulate the dry granules, and pack them separately to obtain the product.

Embodiment 3

[0100] Preparation of tablets:

[0101] Prescription: Qingpi 400g, Curcuma 400g, Cyperus Cyperi 480g, White Mustard Seed 240g, Salvia miltiorrhiza 600g, Astragalus 600g, Weeping grass 600g.

[0102] The extraction process was as described above. The extract is concentrated, dried, crushed and passed through a 80-mesh sieve, the prepared dry powder is added with 5% starch, and suitable 70% ethanol is added to make granules, dried, and the dry granules are sieved through a 20-mesh sieve for granulation. Then add 0.5% magnesium stearate, mix evenly, compress into tablets, and make plain tablets or film-coated tablets.

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PUM

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Abstract

The invention relates to a kind of Chinese traditional medicine compound preparation which can treat chronic cholecystitis, its ingredients, extracting technology, preparing technology, function and indication are also disclosed in the invention. The ingredients of the invention include green tangerine peel, Curcuma aromatica, nut grass galingale rhizome, white mustard seed, danshen root, radix astragali and sedi,herba. The preparation in the invention can treat chronic cholecystitis, stagnation of liver-QI with deficiency of the spleen and humid heat heaping. It has the function of dispersing the depressed liver-energy, invigorating the spleen, cholagogue and getting through the collaterals. The preparing procedure of the invention includes the following steps: pulverizing the Chinese traditional medicine properly; steam distillation; enveloping with beta-cyclodextrin; recirculation with water or alcohol; condensing and drying the extracted solution; adding certain accessories to made pellets, capsules, granules, guttates and other medically acceptable dosages. The advantages of the invention include: sufficient drug sources, simple preparing technologies, obvious curative effect, safe and low toxicity; it's safe and medically reliable.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine compound preparation for treating chronic cholecystitis. Specifically, it is a Chinese patent medicine made from Chinese herbal medicine, its prescription composition, extraction process, preparation preparation process, functions, indications and indications. Background technique: [0002] Chronic cholecystitis is a high incidence and common disease in gastroenterology. Modern studies have shown that gallstones are the main cause of chronic cholecystitis. At present, Western medicine has no effective treatment method for chronic cholecystitis except operation, and the operation method has not been accepted by most patients. In addition to poor curative effect, western medicine also has diarrhea and liver and kidney toxicity side effects. The majority of patients bring great pain and burden. Traditional Chinese medicine believes that chronic cholecystitis belongs to the category of "biliary di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/00A61K9/16A61K9/20A61K9/48A61P1/16
Inventor 孙蓉曹志群吕丽莉尹建伟张作平于晓任海勇衣银萍
Owner 孙蓉
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