The present application discloses a method, system, device and computer-readable storage medium for security-constrained economic scheduling, and establishes an objective function and constraint conditions aiming at realizing dynamic operation reserve demand and considering the operation reserve price and operation reserve plan of generating units , by substituting the given power grid operation reserve demand into the objective function and constraints, calculate the unit output plan and the operation reserve plan, and then use the operation reserve plan to obtain the current power grid operation reserve demand, and compare the current power grid operation reserve demand with the last current power grid Run the backup demand to judge whether the convergence coefficient is met. If not, resubstitute the current power grid operation backup demand into the objective function and constraint conditions to obtain the next power grid operation backup demand, repeat iterations until the convergence coefficient is satisfied, and output the current power grid operation The backup demand and unit output plan reduce the system operation backup level, improve the power availability of the generator set and the operation efficiency of the power grid.