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Health Monitoring System

a health monitoring and monitoring system technology, applied in the field of continuous glucose monitoring, can solve the problems of increasing the risk of serious health problems related to hypoglycemia, long-term complications, and attempts at normalizing glucose concentrations, and achieve the effect of reducing nois

Inactive Publication Date: 2011-12-22
RGT UNIV OF CALIFORNIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0015]In another embodiment the invention provides a method of using a subject machine, programmed-computer or algorithm for processing continuous glucose monitoring (CGM) data and issuing an alert or signal if hypoglycemia is imminent, the method comprising the steps of: (a) receiving and modulating CGM data in a pre-processing module by reducing noise and adjusting for missed data points and shifts due to calibration; (b) receiving data from the pre-processing module in a core algorithm module that then calculates a rate of change to make a hypoglycemia prediction, and determine if hypoglycemia is imminent; and (c) receiving data from the core algorithm in an alarm mode module that then issues an audio or visual alert or warning message or a negative feedback signal to an insulin delivery device if hypoglycemia is imminent.

Problems solved by technology

Chronic elevations, and likely fluctuations, of the blood glucose may result in long term complications (blindness, kidney failure, heart disease, and lower extremity amputations).
Perversely, attempts at normalizing glucose concentrations also increases the risk of serious health issues related to hypoglycemia.
1) the difficulties in correctly estimating the amount of carbohydrates in a meal,
2) missed meal boluses, and
3) anxiety about anticipated hypoglycemia, resulting in patients giving themselves less insulin, especially overnight.
It has always been difficult to achieve compliance with complicated medical regimens, such as the administration of insulin three or more times a day.
As long as diabetes treatment demands constant direct intervention, the vast majority of people with diabetes will not meet treatment goals.

Method used

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Embodiment Construction

[0030]The HMS functions as a process monitoring module that is executed in real time. This section of the control algorithm serves as a safety layer to the device. The zone-MPC algorithm controls the delivery of insulin, while the HMS evaluates the trend of the glucose in a different way in order to provide an extra layer of safety to ensure the health of the subject. The HMS will generate an audible and visual alert to the clinicians and send a text message to the physician in charge with a profile of the current trend and prediction for the upcoming 15 minutes. The key module of the HMS is the low glucose predictor (LGP) that uses a set of constraints to predict the imminent occurrence of hypoglycemia. The relevant variable is glucose concentration, G, assumed to be the CGM measurement. The LGP has three major modules: a pre-processing module to get the CGM data ready for prediction; a core algorithm section to calculate the rate of change, make predictions, and determine if hypog...

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Abstract

A machine for processing continuous glucose monitoring data and issuing an alert if hypoglycemia is imminent has three modules: (a) a pre-processing module that receives and modulates continuous glucose monitoring data by reducing noise and adjusting for missed data points and shifts due to calibration; (b) a core algorithm module that receives data from the pre-processing module and calculates a rate of change to make a hypoglycemia prediction, and determine if hypoglycemia is imminent; and (c) an alarm mode module that receives data from the core algorithm and issues an audio or visual alert or warning message or a negative feedback signal to an insulin delivery device if hypoglycemia is imminent.

Description

CROSS REFERENCE TO RELATED APPLICATION[0001]This application claims priority under 35 U.S.C. §119 from Provisional Application Ser. No. 61 / 357,409, filed Jun. 22, 2010, the disclosure of which is incorporated herein by reference.[0002]This work was supported by grant ROI-DK085628-01 from the National Institutes of Health; the Government has certain rights in this invention.FIELD OF THE INVENTION[0003]The field of the invention is a continuous glucose monitoring.BACKGROUND OF THE INVENTION[0004]Diabetes is a chronic disease only controlled by constant vigilance. Chronic elevations, and likely fluctuations, of the blood glucose may result in long term complications (blindness, kidney failure, heart disease, and lower extremity amputations). Perversely, attempts at normalizing glucose concentrations also increases the risk of serious health issues related to hypoglycemia. Despite the use of insulin infusion pumps and programs that promote intensive diabetes management, the average A1c ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G06F19/00G16H20/60G16H40/63G16H40/67
CPCA61B5/14532A61B5/7275G06F19/3487G06F19/345G06F19/3456G06F19/3418G16H15/00G16H50/20G16H40/67G16H40/63G16H20/60A61B5/746
Inventor DOYLE, III, FRANCIS J.DASSAU, EYALZISSER, HOWARDHARVEY, REBECCA A.
Owner RGT UNIV OF CALIFORNIA
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