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Accelerometer-based method for cardiac function and therapy assessment

a cardiac function and a catheter technology, applied in the field of catheters, can solve the problems of congestive cardiac failure affecting the synchronous beating of the ventricles, the risk of progressive heart failure or sudden death of patients with left ventricular failure, and the patient remains markedly symptomatic, so as to prevent further deterioration of cardiac function, reduce cardiac function, and improve cardiac function

Inactive Publication Date: 2006-05-04
MARCUS FR I +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

Enables reliable prediction of CRT effectiveness, optimal lead placement, and A-V delay optimization, reducing the incidence of ineffective therapy and improving cardiac function in heart failure patients.

Problems solved by technology

Nevertheless, many patients remain markedly symptomatic despite maximal medical therapy.
Furthermore, patients with left ventricular failure are at an increased risk of progressive heart failure or sudden death.
In some heart patients, congestive cardiac failure affects the synchronous beating of the ventricles.
Accordingly, the left ventricle is not able to pump blood efficiently to supply the body with needed oxygen and nutrients.
This greatly reduces the efficiency of the left ventricle in patients whose hearts are already damaged.
Many patients with heart failure have poor electrical conduction in the heart that results in a pattern called left bundle branch block (LBBB) or intraventricular conduction delay.
The delay in aortic valve closure leads to a relative decrease in the duration of left ventricle diastole.
In patients with LBBB, prolonged depolarization or abnormal depolarization may result in regional myocardial contraction into early diastole, causing a delay of mitral valve opening with prolongation of left ventricle isovolumic relaxation time of up to 300% and shortened left ventricle filling time.
Further, left ventricle intraventricular conduction delay may add significantly to dyssynchrony, particularly in ischemic heart disease.
While the results have been positive, most studies have shown that approximately 30% of patients do not obtain any measurable benefit from the therapy.
Yet, the exact and best position for each catheter position is difficult to determine at the time of insertion.
In fact, there are no physiological means to determine the best site at the time of lead placement except possibly the use of echocardiography, which is time consuming and poses a problem in keeping the operative field sterile.
In addition, it is difficult to predict the effectiveness of CRT before the insertion of the cardiac pacing device.
However, the decrease in the QRS duration does not correlate well with the improvement of cardiac function in some patients.
However, these parameters cannot be evaluated in real time and do not provide information that physicians need to know at the time of lead and device implantation to determine if the patient will benefit from CRT.
Another problem encountered, particularly with the use of dual-chamber pacemakers, is the proper setting of the so-called “A-V delay interval.” Basically, the A-V delay interval refers to the time interval between a ventricular stimulation pulse and a preceding atrial depolarization.
Because the sequence of atrial and ventricular pacing is vital to the efficiency of the heart as a pump, a non-optimal A-V delay interval can seriously impact heart performance.

Method used

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  • Accelerometer-based method for cardiac function and therapy assessment
  • Accelerometer-based method for cardiac function and therapy assessment
  • Accelerometer-based method for cardiac function and therapy assessment

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Embodiment Construction

[0036] The invention relates in general to a method for determining a change in function of a patient's heart that includes the steps of collecting seismocardiographic (SCG) data from an external surface of a patient corresponding to a heart motion of the patient's heart; determining a hemodynamic parameter based on the SCG data; and comparing the parameter with a predetermined measure of cardiac performance.

[0037] Seismocardiography (SCG) is a method derived from the field of seismology to non-invasively measure compression waves generated by myocardial motion. These compression waves are measured by a low frequency accelerometer placed on the sternum, and recorded chest movement induced by ventricular motion is analyzed by software in a computer. The seismograph tracings identify cardiac time intervals that correlate with the opening and closing of cardiac valves, left ventricular (LV) systolic and diastolic time intervals, isovolumetric contraction and relaxation intervals, LV f...

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Abstract

A method for determining a change in function of a patient's heart that includes the steps of collecting seismocardiographic (SCG) data corresponding to a heart motion of the patient's heart; determining a hemodynamic parameter based on the SCG data; and comparing the parameter with a predetermined measure of cardiac performance. The system used with the method includes one or more accelerometer sensors, a computer data analysis module, and may also include a 2D and 3D visual graphic display of analytic results, i.e. a Ventricular Contraction Map.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] This application is a continuation-in-part of, and claims priority to, U.S. patent application Ser. No. 10 / 629,881, filed on Jul. 29, 2003, which claims priority to U.S. Provisional Patent Application Ser. No. 60 / 399,028, which was filed on Jul. 29, 2002 by the same inventors.BACKGROUND OF INVENTION [0002] 1. Field of Invention [0003] The present invention relates generally to accelerometer use and to methods for determining a change in function of a patient's heart. [0004] 2. Description of Related Art [0005] Heart failure afflicts about twenty-five million people worldwide, with about two million new cases diagnosed each year. In the United States, hospitalization for heart failure amounts to more than 6.8 million days a year, and the total cost of treatment is more than $38 billion annually, which is increasing as the population ages. The prevalence of congestive cardiac failure is also increasing due to improved survival from both m...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N1/368A61BA61B5/11A61N1/00A61N1/05A61N1/362A61N1/365
CPCA61B5/1107A61N1/3627A61N1/36542A61N1/3682A61N1/3684A61B5/7217A61B5/6869A61N1/36842A61N1/36843
Inventor MARCUS, FRANK I.HE, DING SHENG
Owner MARCUS FR I
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