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Yanhouqing preparation for treating throat disease and its preparation method and quality control method

A technology for throat diseases and preparations, which is applied in the field of throat clearing preparations and its preparation method and quality control, and can solve the problems of high bioavailability, inconvenient taking of granules, and poor taste

Inactive Publication Date: 2007-05-02
BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a kind of throat clearing preparation for the treatment of throat disease and its preparation method and quality control method; The present invention provides dosage forms such as dripping pills and dispersible tablets against the prior art, which not only solves the inconvenience and problems of taking granules The problem of poor taste, and good disintegration, high bioavailability; the preparation method provided by the present invention can effectively prepare the required preparations, and ensure that the production process of the obtained preparations is scientific and reasonable; the quality control method provided can be submitted to relevant The production and testing institutions of the company provide testing indicators, testing methods, technical methods, etc., in order to better control the quality of the preparation, ensure the safety of the drug, better guide the production, and make the production process control more strict and reasonable. To enable consumers to fully understand the quality of the product

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0209] Example 2 of the present invention: 105.5g of nine lion grass, 63g of cinnabar root, 79g of salicylate root, 79g of glutinous rice root, 31.5g of golden fruit olive, 63g of bellflower, 79g of peppermint, 2.5g of menthol

[0210] Take nine lion grass, cinnabar root, water bayberry root, glutinous rice vine root, golden fruit olive, platycodon grandiflorum, mint, steam distillation to extract volatile oil, the distilled aqueous solution is collected in another device, the dregs of the medicine are decocted for 1.5 hours, filtered, and Combine the above aqueous solutions, concentrate under reduced pressure to a clear paste with a relative density of 1.10 to 1.12 at a relative density of 60°C, add ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter, and recover the filtrate under reduced pressure below 80°C for ethanol concentration, Dry, add menthol, mix evenly and pulverize into fine powder, add matrix PEG4000 according to extract powder: matri...

Embodiment 3

[0211] Example 3 of the present invention: 105.5g of nine lion grass, 63g of cinnabar root, 79g of salicylate root, 79g of glutinous rice root, 31.5g of golden fruit olive, 63g of bellflower, 79g of peppermint, 2.5g of menthol

[0212] Take nine lion grass, cinnabar root, water bayberry root, glutinous rice vine root, golden fruit olive, platycodon grandiflorum, mint, steam distillation to extract volatile oil, the distilled aqueous solution is collected in another device, the dregs of the medicine are decocted for 1.5 hours, filtered, and Combine the above aqueous solutions, concentrate under reduced pressure to a clear paste with a relative density of 1.10 to 1.12 at a relative density of 60°C, add ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter, and recover the filtrate under reduced pressure below 80°C for ethanol concentration, Dry, add menthol, mix evenly and pulverize into fine powder, add matrix PEG4000 according to extract powder: matri...

Embodiment 8

[0221] Example 8 TLC identification of salicylate root in dropping pills

[0222]Take 3.0g of this product powder, add methanol 50ml, ultrasonically treat for 30 minutes, filter, evaporate the filtrate to dryness, add 20ml of water to dissolve the residue, add ethyl acetate and shake and extract twice, 20ml each time, combine the ethyl acetate solution, evaporate Dry, add methanol 1ml to the residue to dissolve, as the test solution. Take another negative sample (water-deficient Myrica rubra root), and make a negative sample solution in the same way. Then take 2 g of the reference drug of Myrica rubra root, add 50 ml of ethyl acetate, ultrasonically treat it for 60 minutes, filter, evaporate the filtrate to dryness, add 1 ml of methanol to the residue to dissolve, and use it as the reference drug solution. According to the thin-layer chromatography test, draw 10 μl of each of the above two solutions, spot them on the same silica gel G thin-layer plate, use chloroform-acetone ...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill, dispersing tablet, or micropill for treating thirst, painful throat, hoar seness, cough, etc is prepared from 8 Chinese- medicinal materials including Japanese peristrophe herb, coral ardisia root, thinleaf adina root, etc. Its preparing process and quality control method are also disclosed.

Description

technical field [0001] The invention relates to a throat clearing preparation for treating throat diseases, a preparation method and a quality control method thereof, and belongs to the technical field of traditional Chinese medicines. technical background [0002] The throat is the first line of defense of the human respiratory system. In recent years, due to the hazards of air pollution and tobacco poisoning, the influence of occupational factors, the stimulation of drinking, dust and other factors, throat diseases are on the rise. Especially in the dry winter, air pollution and dust particles increase greatly, which can easily induce throat diseases. Inflammation leads to hoarseness, aphonia, dry throat, itchy throat, sore throat, unpleasant sputum, and foreign body sensation in the throat, often accompanied by the habitual reaction of "squeak, click". These lingering feelings, if not diagnosed and treated in time , prevention, easy to repeat, very stubborn, it is likely...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/00A61P11/04G01N30/02G01N30/90G01N33/15
Inventor 于文风
Owner BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
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