Mannitol contrast medium

Abstract

The invention relates to a contrast-medium used in intestinal canal CT check. Wherein, it is formed by 20% manna sugar injection at 250ml, 76% cardiografin injection at 20ml, and water at 500ml; the manna sugar is promoting urination dewater agent, to be orally taken, to improve the penetrate pressure in intestinal canal, to make the liquid of organism slim and capillary blood enter into bowel lumen to improve the liquid capacity of bowel lumen, to express the ill part.

Description

technical field [0001] The invention is a contrast agent used in intestinal CT examination. technical background [0002] Intestinal diseases are common and frequently-occurring diseases of the digestive system. Enteritis, tuberculosis, and tumors are common clinically, among which colon tumors are the most common. At present, there are many clinical examination methods for intestinal diseases, including endoscopy, small bowel intubation, barium enema and B-ultrasound, etc., but due to the influence of various factors, the examination results are not ideal. In recent years, CT has been increasingly used Intestinal examination, but the reasonable choice of oral contrast agent has not been well resolved. For this reason, scholars at home and abroad have done a lot of research, and they all agree that an ideal contrast agent should meet the following requirements and conditions: 1. Easy to be accepted by patients; 2. Uniform, stable, not absorbed by the intestinal tract and no...

AI Technical Summary

Problems solved by technology

At present, there are three kinds of intestinal CT contrast agents commonly used clinically: 1. High-density contrast agents, which are widely used in clinical practice are 2%-3% organic iodine solutions, such as diatrizoate meglumine, etc., 1%-2% medical Barium sulfate suspension is also used. This contrast agent is characterized by homogeneity, stability, and good contrast. It is not easily absorbed by the intestinal tract. For example, it is more acceptable to patients when combined with other beverages or spices. The disadvantage is that the intestinal wall is not well displayed. , the filling intestinal segment is limited, and the filling time is difficult to grasp, etc., which are often used in routine abdominal CT examinations; 2. Isodensity contrast agents (based on the density of water, such as drinking water or other beverages, etc.), the biggest advantage is convenience and ease of use by patients. Accepted, compared with high-density contrast agents, the ability to display the intestinal wall is significantly higher than the former, and is similar to lipid contrast agents. The disadvantage is that it needs to be taken orally in a large amount, and patients are not easy to tolerate (especially severely weak patients), and it is harmful to the small intestine. Unsatisfactory inspection results; 3. Low-density contrast agents: mainly lipids and gases. Lipid contrast agents are usually mixed with 125%-25% emulsified corn oil and flavoring agents. Satisfactory, the main disadvantage is that patients are not easy to accept, some patients have adverse reactions such as nausea, vomiting, abdominal pain and diarrhea, and patients with acute pancreatitis, diabetes and hyperlipidemia should not use it

Gas contrast agent shows better intestinal wall than high-density contrast agent, but not as good as water and lipid, and the density contrast between gas and surrounding soft tissue is too large, which is prone to artifacts