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Method for preparing Chinese herb medicine utilizing enzyme preparation

A technology of Chinese herbal medicine and enzyme preparation, which is applied in the field of preparation of Chinese herbal medicine by using enzyme preparation, which can solve the problems of large energy and manpower consumption, reduced curative effect, slow absorption, etc., and achieve the effects of reducing pharmaceutical costs, increasing extraction rate, and convenient application

Inactive Publication Date: 2011-05-18
FUZHOU ENSURE ENZYME ENG DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the backwardness of the traditional Chinese medicine production process, only a small amount of active ingredients in the medicinal materials can be extracted, resulting in a low extraction rate of active ingredients; many beneficial vitamins, trace elements, and volatile oils have been destroyed and volatilized in the high-temperature, high-pressure production process. As a result, the potency of the medicine is weakened, which affects the improvement of the efficacy of the medicine; in addition, the active ingredients generally stay in the state of macromolecules, and can only play a role outside the cells of the diseased body, and the absorption is slow, and the curative effect is correspondingly reduced; at the same time, it consumes a lot of energy and manpower. , produce "three wastes", which cause a serious waste of Chinese herbal medicine resources, and affect economic benefits and environmental protection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Ganoderma lucidum: 1 kg.

[0013] Prepare multienzyme mixture: 10g of cellulase, 5g of pectinase, 5g of protease, 3g of peptone, 3g of glucose, 10ml of lactic acid, 3g of yeast extract, 5g of red yeast rice, 5g of yeast, and make 200ml with water.

[0014] Enzyme promoters added to the multienzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0015] Take 1 kg of Sessile Ganoderma lucidum, dry it at 50-60°C, crush it to 20 mesh, add 3 kg of pure water, adjust the pH value to 4.5-6.5 with lactic acid and soak for 8 hours, then add 2 kg of pure water to adjust the pH to 4.0- 5.0 Add 200ml of multienzyme mixture, stir evenly, put in an enzymatic hydrolysis tank at 37°C for 48 hours, stir and oxygenate 3 times a day, press and filter after the end, wash the filter residue twice with 50-60°C pure water and filter , combined filtrate, concentrated and dried into powder, sterilized packaging is the finished product.

[0016] In the case of the same amount of ...

Embodiment 2

[0020] Licorice: 1 kg.

[0021] Prepare multienzyme mixture: 10g of cellulase, 5g of pectinase, 5g of protease, 3g of peptone, 3g of glucose, 10ml of lactic acid, 3g of yeast extract, 5g of red yeast rice, 5g of yeast, and make 200ml with water.

[0022] Enzyme promoters added to the multienzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0023] Take 1 kg of licorice and dry it at 50-60°C, crush it to 20 mesh, add pure water, adjust the pH value to 4.5-6.5 with lactic acid and soak for 8 hours, then add pure water until the medicinal material forms a ball in your hand, release it immediately Disperse; adjust the pH to 4.0-5.0, add 200ml of multienzyme mixture, stir evenly, put it in an enzymolysis tank at 37°C for 48 hours, stir and oxygenate 3 times a day, press and filter after the end, and filter the residue with 50- Wash with purified water at 60°C for two times and filter, combine the filtrates, concentrate and dry them into powder, and sterilize the p...

Embodiment 3

[0027] Astragalus: 1 kg.

[0028] Prepare multienzyme mixture: 10g of cellulase, 5g of pectinase, 5g of protease, 3g of peptone, 3g of glucose, 10ml of lactic acid, 3g of yeast extract, 5g of red yeast rice, 5g of yeast, and make 200ml with water.

[0029] Enzyme promoters added to the multienzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0030] Take 1 kg of astragalus and dry it at 50-60°C, crush it to 20 meshes, add 3 kg of pure water, adjust the pH value to 4.5-6.5 with lactic acid and soak for 8 hours, then add pure water until the medicinal materials are grasped into a ball in the hand, put Open and disperse; adjust the pH to 4.0-5.0, add the multi-enzyme mixture, stir evenly, and put it in the enzymolysis tank at 37°C for 48 hours, stir and oxygenate 3 times a day, press and filter after the end, and filter the residue with 50 ~ 60 ℃ pure water washed twice and filtered, combined filtrate, concentrated and dried into powder, sterilized packaging is ...

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Abstract

The present invention relates to a method for preparing Chinese herbal medicine by using enzyme preparation. It is extracted by utilizing biochemical action. It is characterized by that it utilizes catalystic reaction of enzyme and fermentation action of microorganism, according to different medicinal material or its composition, said invention selects the multienzyme body containing pectic enzyme, alpha-diastase and proteinase as enzyme preparation and utilizes said enzyme preparation to make the Chinese herbal medicine undergo the sufficient enzymolysis and fermentation so as to obtain the invented Chinese herbal medicine product. The Chinese herbal medicine according to the invention has a good curing effect, and has no pollution. It is convenient to use, rapid to effect, low cost and has no side effect. It has wide application prospect.

Description

technical field [0001] The invention relates to a technology for developing and utilizing enzymes in the field of biotechnology, in particular to a method for preparing Chinese herbal medicines by using enzyme preparations (that is, a method for extracting effective medicinal ingredients and functional substances from Chinese medicinal materials by enzymatic hydrolysis). technical background [0002] As we all know, traditional Chinese medicine is a great treasure house of the Chinese nation. It not only has a complete and systematic medical theory, but also has countless prescriptions for treating various diseases. These prescriptions include various traditional Chinese medicines including Chinese herbal medicines. A large number of Chinese herbal medicines come from the roots, stems, leaves, fruits, and flowers of plants, and their effective medicinal ingredients are mainly various natural chemical substances in plants. However, 50-75% of the dry weight of the plant is cel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P1/00C12N9/00A61K36/00
Inventor 林陆山汪奋生
Owner FUZHOU ENSURE ENZYME ENG DEV
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