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Method for extracting active substances from cow colostrums and equipment therefor

A technology for active substances and colostrum, which is applied in the field of extracting active substances from bovine colostrum and its equipment, can solve the problem that the potential of ion exchange and adsorption separation has not been fully exerted, the comprehensive utilization of resources needs to be improved, and the purity and activity are low. problems, to achieve the effect of saving washing water consumption, reducing volume and consumption, and simple operation

Inactive Publication Date: 2006-12-27
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (1) The product variety is relatively single, mainly developing immunoglobulin (IgG)
[0005] (2) The comprehensive utilization of resources still needs to be improved
There are many functional components in bovine colostrum, and the current technology is generally aimed at a certain target protein to be extracted, such as immunoglobulin, while less consideration is given to other functional components rich in colostrum, resulting in waste of resources
[0006] (3) The grade of the product is still relatively low, like domestic IgG extracted from bovine colostrum, due to the problem of separation technology, its purity and activity are still relatively low, so it can only be used in ordinary food, which greatly reduces the value of the product itself
However, the potential of ion exchange and adsorption separation has not been fully exploited due to the lack of a truly continuous process technology that is feasible in industry

Method used

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  • Method for extracting active substances from cow colostrums and equipment therefor
  • Method for extracting active substances from cow colostrums and equipment therefor
  • Method for extracting active substances from cow colostrums and equipment therefor

Examples

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Effect test

Embodiment

[0038] Embodiment: the present embodiment extracts the active substance in bovine colostrum, adopts the following steps:

[0039] 1. Select raw materials:

[0040] The raw material is the milk of the cow within 6 times after giving birth to the calf.

[0041] The Lf content in bovine colostrum is generally 10 to 100 times higher than that of ordinary milk. But bovine colostrum also has its shortcomings: the composition is more complex than ordinary milk, and sometimes bloodshot; it is viscous, easy to agglomerate, and volatile; it has peculiar smell. Since the fat in cow's milk will seriously affect the ion exchange chromatography process, the colostrum must be strictly defatted.

[0042] 2. Defatting of colostrum

[0043] 1) Filtration: The bovine colostrum is filtered through 16 layers of gauze before being frozen and centrifuged to degrease.

[0044] 2) Frozen centrifugal degreasing: In order to prevent the protein in bovine colostrum from being denatured due to tempera...

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Abstract

The present invention relates to a method for extracting active substances from cow colostrums and its equipment. The invention uses continuous ion exchange equipment to extract active substances from cow colostrums. The process simplifies cow colostrums separation steps, increases its yield and purity, reduces separation cost for industrialization and improves cow colostrums resource utility ratio. The present invention also provides a kind of equipment, which realizes continuous ion exchange, increases yield and purity, reduces separation cost for industrialization and reaches the target of comprehensive utilization of cow colostrums.

Description

technical field [0001] The invention relates to an extraction method and equipment used for extracting active substances, in particular to a method and equipment for extracting bovine colostrum active substances. Background technique [0002] Scientific research has confirmed that bovine colostrum is one of the biological resources with the most abundant immune factors in nature, including important immune factors and growth factors, such as immunoglobulin (IgG), lactoferrin (Lf) and insulin-like growth factor ( IGF), etc., the content is 10-100 times higher than that of regular milk. These physiologically active ingredients have a series of biological functions such as immune regulation, delaying aging, promoting growth and development, and inhibiting tumors. They can not only manufacture functional foods, but also have great potential to develop natural active biological drugs. However, the development of colostrum resources has just begun, mainl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/20A61P37/02A23L1/30A23L33/17A23L33/19
Inventor 吴绵斌解大斌孔繁智
Owner ZHEJIANG UNIV
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