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Solid water soluble propolis composition and preparation method thereof

A technology of water-soluble propolis and composition, which is applied in the direction of food preparation, drug combination, non-effective ingredients of polymer compounds, etc., can solve the problems of natural propolis such as poor taste, reduced antibacterial property, and functional discount, and achieves improved taste and stable properties , the effect of promoting tissue regeneration

Inactive Publication Date: 2006-12-20
魏春华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, the water-soluble propolis sold in the market is purified by ethanol, and emulsifiers (mostly Tween 80) or sodium hydroxide are added to the propolis. After adding additives, the safety of food is affected. The experiment also proved that the function of "water-soluble propolis" after adding emulsifiers is greatly reduced, and the antibacterial property is reduced by more than ten times; in addition, the taste of natural propolis is extremely bad, with a strong bitter taste, which is difficult for ordinary consumers to accept, so the dosage form is changed Or package propolis with other auxiliary materials to improve the taste of propolis. It is the responsibility of scientists to produce propolis that is acceptable to consumers and has significant curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Wax-removing propolis raw material (hair glue) 100g, heat in a water bath to remove beeswax, dissolve it with 200ml of absolute ethanol by its weight, filter, take the supernatant, and extract the supernatant with about 50ml of absolute ethanol that is 1 times the volume of the propolis precipitate , combined the supernatant, discarded the residue, evaporated and recovered about 100ml of ethanol solvent, obtained about 200g of propolis ethanol jelly, which was converted into a dry weight of about 60 grams.

[0020] Use the purified propolis to convert it into dry powder and β-cyclodextrin, and mix it thoroughly at a weight ratio of 1:15, that is, 200g of propolis ethanol jelly (about 60 grams of propolis dry weight) and 940 grams of β-cyclodextrin The solid water-soluble propolis composition of the present invention can be obtained by vigorous stirring or rolling inclusion of dextrin, hot air drying, crushing, and sieving (with a mesh number of 70-100 mesh).

[0021] Th...

Embodiment 2

[0023] 100g of wax-removing propolis raw material (maojiao) is dissolved in 400g of absolute ethanol by its weight, filtered, and the supernatant is taken, and the supernatant is extracted with absolute ethanol of 1 times the volume of the propolis precipitate, and the supernatant is combined and discarded. Residue is removed, part of the ethanol solvent is recovered by evaporation, and about 200 g of propolis ethanol jelly is obtained, which is converted into a dry weight of about 60 grams.

[0024] Convert the purified propolis into dry powder and hydroxypropyl β-cyclodextrin (cyclodextrin derivative), and fully mix it in a weight ratio of 2: 17, that is, 510 grams of hydroxypropyl β-cyclodextrin, Vigorously stirred or rolled and clathrated, dried with hot air, pulverized, and sieved (70-100 meshes), the solid water-soluble propolis composition of the present invention can be obtained containing 11% dewaxed and purified propolis and 89% propolis Hydroxypropyl beta-cyclodextr...

Embodiment 3

[0026]100g of wax-removing propolis raw material (hair glue), dissolved in 300g of dehydrated ethanol, filtered, and supernatant was taken, then extracted with dehydrated ethanol of 1 times the volume of propolis precipitate, combined supernatant, and discarded residue , part of the ethanol solvent is recovered by evaporation to obtain about 200g of propolis ethanol jelly of purification, which is converted into about 60 grams of dry weight.

[0027] Use the purified propolis to convert it into dry powder and α-cyclodextrin or γ-cyclodextrin, and mix it thoroughly at a weight ratio of 2:15, that is, 450 grams of α-cyclodextrin or γ-cyclodextrin, vigorously stir or grind Press clathrate, dry with hot air, pulverize, sieve (the mesh number is 70-100 mesh), can obtain the propolis that contains 12% dewaxing and purifying in the solid water-soluble propolis composition of the present invention and 88% α-cyclopaste Alcohol or γ-cyclodextrin.

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PUM

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Abstract

The invention relates to a solid soluble propolis compound and relative preparation, wherein said invention is formed by packing anhydrous alcohol with beta- cyclodextrin (cyclodextrin or cyclodextrin derivant) to be extracted into propolis; it uses pastern bath to heat and remove wax, and uses anhydrous alcohol to extract the effective component of propolis, to be filtered, deposited, and vaporized into part alcohol dissolvent; then packing the cyclodextrin or cyclodextrin derivant, to be dried, broken and screened, to obtain the solid soluble propolis compound. The invention can effectively keep effect components of propolis, and the cyclodextrin can increase the solubility of effect components. The invention can be made into powder, sheet, drop, capsule and pastern, etc.

Description

technical field [0001] The invention belongs to the field of health food, in particular to a method for preparing solid water-soluble propolis Background technique: [0002] There are many invention patents about the preparation of water-soluble propolis, for example: Chinese patent (CN94118328.9 preparation method of water-soluble propolis) adopts glycerin soaking to obtain water-soluble propolis. Chinese patent (CN95117897.0 propolis powder and its preparation process), the powder includes purified propolis and superfine silicon dioxide. Chinese patent (CN00137060.X a process for purifying propolis) adopts ethanol extraction, drying and crushing to prepare propolis. Chinese patent (CN03141394.3 water-soluble propolis and preparation method thereof), it consists of propolis, polyethylene glycol and distilled water. Chinese patent (CN200380104801.2 Quaternary Composition Containing Propolis as Active Substance), uses propolis active substance, hydrophilic carrier and one i...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61K47/40A61P1/14A23L1/076A23L21/20A61K35/644
Inventor 魏春华
Owner 魏春华
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