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Medicine preparation for preventing and treating heart brain and kidney blood vessel diseases

A drug preparation and renal blood vessel technology, which is applied in cardiovascular system diseases, drug combinations, urinary system diseases, etc., can solve the problems of single target, unclear effect, and low bioavailability

Inactive Publication Date: 2006-10-25
GUANGXI MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the former is effective, but the target is relatively single, although the latter is a compound, but most of the preparations are rough, the role of each component (according to modern medical theory) is not clear, the bioavailability is low, and the drug effect is poor. Recognized, research on disassembly and formulation improvement is still needed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Calculated by weight components: take 153g of tea polyphenols (TP, purity 98%), 25g of ginkgo extract (Egb761, total flavonoids / total lactones=24 / 6) according to the ratio of 15:2.5:5:1, and total Saponin (PNS, purity 90%) 56g, Danshensu (DS, 3% needle extract) 333g (the above four medicines were all purchased from Chengdu Huagao Natural Medicine Co., Ltd.) and mixed evenly (the amount of each component was converted according to the purity ratio) , get dry powder. Calculated by weight components: take by weighing 500g of dry medicine powder and 25g of starch in a ratio of 1:0.05 and mix evenly, use 4ml of edible ethanol with a concentration of 70% as a wetting agent to make wet granules, dry at about 37°C, and make 1000 capsules, pass the inspection, and pack separately to obtain the finished product of Xinnao Shenkang Capsules.

[0034] Usage and dosage: Take orally, 2 to 4 capsules each time, 3 times a day.

[0035] Storage: sealed, in a cool dry place.

Embodiment 2

[0037] Calculated by weight components: take 102g of tea polyphenols (TP, purity 98%), 25g of ginkgo extract (Egb761, total flavonoids / total lactones=24 / 6) according to the ratio of 50:12.5:15:10, and total Saponin (PNS, purity 90%) 33g, Danshensu (DS, 3% needle extract) 667g (the above four medicines were all purchased from Chengdu Huagao Natural Medicine Co., Ltd.) and mixed evenly (the amount of each component was converted according to the purity ratio) , get dry powder. Calculated by weight components: Take 500g of dry medicine powder and 50g of starch in a ratio of 1:0.1 and mix them evenly, use 6ml of edible ethanol with a concentration of 90% as a wetting agent to make wet granules, dry at about 37°C, and make 1060 capsules , passed the inspection, and packaged separately to obtain the finished product of Xinnao Shenkang Capsules.

[0038] Usage and dosage: Take orally, 2 to 4 capsules each time, 3 times a day.

[0039] Storage: sealed, in a cool dry place.

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PUM

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Abstract

The present invention provides a compound preparation for preventing and curing angiocardiopathy, cerbrovascular disease and renal vascular disease. It is made up by using green tea, ginkgo leaf, notoginseng stem and leaf, salvia root, active component tea-polyphenol (TP) extracted from Chinese angelica root, ginkgo extract (Egb 761), notoginseng total saponin (PNS) and danshenzu (DS) as main raw material through a certain preparation process.

Description

technical field [0001] The present invention relates to a pharmaceutical preparation for preventing and treating cardiovascular, cerebrovascular and vascular diseases made of Chinese herbal medicine extracts as the main raw material. Low toxicity natural antioxidant. Background technique [0002] In recent years, studies have found that the imbalance between oxidative stress and antioxidant mechanisms leads to excess oxygen free radicals (OFR) in the human body and some common clinical cardiovascular and cerebrovascular diseases such as coronary heart disease, stroke, arrhythmia, myocardial infarction, Alzheimer's disease, Parkinson's paralysis is closely related to the occurrence and damage of renal tissue lesions such as nephritis, acute renal failure, and rejection after renal transplantation. According to statistics, among the more than 1,000 small-molecule drugs marketed worldwide from 1982 to 2002, 55% were derived from natural products or their derivatives, of which ...

Claims

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Application Information

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IPC IPC(8): A61K36/16A61K31/192A61K31/353A61K31/704A61K36/537A61P9/00A61P13/12
Inventor 梁钢
Owner GUANGXI MEDICAL UNIVERSITY
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