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Chinese medicine composition new use

A composition and drug technology, applied in the field of pharmacy, can solve the problems of inability to treat chronic renal failure, inability to treat acute renal failure, etc.

Active Publication Date: 2006-08-09
珠海保税区丽珠合成制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] Those of ordinary skill in the art know that conventional drugs for the treatment of acute renal failure, such as arsenic trioxide injection, etc., cannot treat chronic renal failure; and drugs such as Shenqi Dihuang Decoction for the treatment of chronic renal failure cannot treat acute renal failure. functional failure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 8

[0091] Embodiment 8: Extraction and separation are prepared into large-capacity injection

[0092] Put 150g of Rhizoma Chuanxiong, 150g of Epimedium, 200g of Angelica, 150g of Alisma and 70wt.% ethanol in a multifunctional extraction tank, and soak overnight. Reflux extraction twice, each time for 1.5 hours, filter to obtain medicinal residue I and medicinal liquid I, keep medicinal residue I, medicinal liquid I is placed in a vacuum concentration pot, and concentrated to obtain concentrated solution A (80°C, d=1.10), Label, indicate product name, batch number, date, etc.

[0093] Add 400g of Astragalus membranaceus, 200g of raw land, and 150g of Poria cocos into 3200ml of water for injection and soak for 1 hour, add the above-mentioned reserved medicinal residue I, add 3200ml of water for injection and decoct twice, each time for 1.5 hours, filter, combine the filtrate, discard the medicinal residue, and combine Put the liquid in a three-effect concentrator, stop concentrating...

Embodiment 9

[0096] Put 200g of Rhizoma Chuanxiong, 150g of Epimedium, 220g of Angelica, 150g of Rhubarb and 70wt.% ethanol in a multifunctional extraction tank, and soak overnight. Reflux extraction twice, each time for 2.0 hours, filter to obtain medicinal residue I and medicinal liquid I, keep medicinal residue I, medicinal liquid I is placed in a vacuum concentration pot, and concentrated to obtain concentrated solution A (80°C, d=1.10), Label, indicate product name, batch number, date, etc.

[0097] Add 450g of astragalus, 205g of raw land, 185g of Poria cocos, 155g of white peony, 185g of Alisma, 5g of Panax notoginseng into 3200ml of water for injection and soak for 1 hour, add the above-mentioned reserved medicinal residue I, add 3200ml of water for injection and decoct twice, each time for 1.5 hours, Filter, combine the filtrates, discard the dregs, put the combined solution in a three-effect concentrator, stop concentrating when the specific gravity is 1.12, let cool to room temp...

Embodiment 10

[0099] Example 10: Preparation of 20ml freeze-dried powder injection

[0100] (1) Get Rhizoma Chuanxiong 200g, Epimedium 185g, Angelica Sinensis 200g, Rhubarb 150g, the total weight of each component above is 7 times 60wt.% ethanol, heating and reflux extracting 2 times, each 2.0 hours, filtering to get medicinal residue 1 and medicinal Liquid I, keep the dregs I.

[0101] (2) Add 450g of astragalus, 15g of raw land, 100g of Poria cocos, 155g of white peony root, 15g of Alisma, and 75g of Panax notoginseng into 3200ml of water for injection and soak for 1 hour, add the above-mentioned reserved medicinal residue I, add 3200ml of water for injection and decoct twice, After 1.5 hours, filter and combine the filtrates to obtain the extract composition. Take 10g of the extraction composition, add an appropriate amount of water for injection to dissolve, add 2.25g of sodium chloride, adjust the volume to 250ml with water for injection, add an appropriate amount of charcoal for inje...

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PUM

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Abstract

The invention relates to a new drug combination and the new use thereof, and it is composed of the following raw materials in weight shares: Chuanxiong 15-200, Membranous Milkvetch Root 40-450, Chinese Angelica Root 20-220, Epimedium Herb 15-185, dried rehmannia root 15-205, Oriental Waterplantain Rhizome 15-185, and Fuling 15-185. And it has functions of curing acute kidney prostration and strengthening immunity and resisting fatigue.

Description

technical field [0001] The present invention relates to a class of pharmaceutical composition, its preparation method and its application, especially the application in the field of pharmacy. Background technique [0002] Acute renal failure refers to a type of acute uremic syndrome in which renal function damage is caused by various reasons, blood urea nitrogen and creatinine rise, and water and electrolyte disorders occur. The etiology is: acute hypovolemia and peripheral circulatory failure caused by various reasons. Mainly (1) toxic substances, the body's immune response to drugs, and severe damage to the kidneys from infection or disease such as acute glomerulonephritis, causing them to fail; (2) sudden drop in blood pressure in severe burns, severe Bleeding (for example, from crushing trauma), or heart attack, etc. lead to abnormal blood supply, which seriously damages the kidneys; (3) blockage somewhere in the urinary tract, which suddenly and completely blocks the f...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P13/12A61P37/04
Inventor 孙虹解荷芝陈剑胡菊华陈春贵
Owner 珠海保税区丽珠合成制药有限公司
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