Ointment of diminishing gore and preparing method
A technology for removing blood stasis and ointment in the blood house, applied in the directions of anti-inflammatory agents, ointment delivery, pharmaceutical formulations, etc., can solve the problems such as the disclosure of the preparation method of ointment that has not been seen for external use.
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Embodiment 1
[0166]Embodiment 1: Take 10 times of the prescription amount, decoct with water twice, use 8 times the amount of water for the first time, decoct for 2 hours, use 6 times the amount of water for the second time, decoct for 2 hours, filter, and combine the filtrates , concentrated under reduced pressure to a relative density of 1.25, cooled to room temperature, added ethanol to make the alcohol content 70%, stirred evenly, allowed to stand for 12 hours to precipitate, took the supernatant to recover ethanol, concentrated under reduced pressure to a thick mixture with a relative density of 1.40 The paste was vacuum-dried at 65° C. to obtain 2.7 kg of dry matter, which was pulverized and passed through a 100-mesh sieve to obtain 2.65 kg of powder. Add 3 times the amount of honey, stir evenly to become a paste, then add 20% sesame oil, fully mix into a paste, get 12.5kg, pack in 10g per bag, and get ointment (every 10 grams of ointment is equivalent to crude drug 10.8 g). Or add ...
Embodiment 2
[0167] Embodiment 2: get 10 times of prescription quantity, extract 2 times with 80% ethanol, 8 times of quantity for the first time, extract 1 hour, use 5 times of quantity water for the second time, extract 1 hour, filter, collect filtrate, reduce Concentrate under reduced pressure to a relative density of 1.15, cool to room temperature, add 1 times the amount of ethyl acetate to extract twice, stand and separate layers, take the upper layer to recover ethyl acetate, concentrate under reduced pressure to a thick paste with a relative density of 1.40, vacuum Dry at 65°C to obtain 1.35kg of dry product, pulverize and pass through a 100-mesh sieve to obtain 1.32kg of powder. Add 3 times the amount of honey, stir evenly to be a paste, then add 20% sesame oil, fully mix into a paste, get 6.2kg, pack in 10g per bag, and get ointment (every 10 grams of ointment is equivalent to 21.7 crude drugs g). Or add 8 times the amount of pressure-sensitive adhesive butyl acrylate and mix eve...
Embodiment 3
[0168] Embodiment 3: Get 10 times of prescription quantity, superfine pulverize into the superfine powder of particle diameter≤10 microns on superfine pulverizer, obtain 12.6kg. Add 3 times the amount of honey, stir evenly to be a paste, add 20% sesame oil, fully mix into a paste, get 59.3kg, pack in 10g per bag, and get ointment (every 10 grams of ointment is equivalent to crude drug 2.27 g). Or add 8 times the amount of pressure-sensitive adhesive butyl acrylate and mix evenly to obtain 111.1 kg of paste, which is directly coated on a certain size interlining cloth at 120°C to make a black plaster hard plaster (each 10 grams of paste is equivalent to in crude drug 1.22g). Or add 30% laurocapram and 10 times the amount of substrate, the ratio of polyvinyl alcohol PVA, glycerin, and silica gel is 5:2:8, mix well and evenly into a paste, get 135.8kg, and apply it on a certain size On the interlining cloth, the surface of the paste is covered with a protective film made of pol...
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