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Compound liver-benefiting dropping pill for treating hepatitis and its preparing method

A technology of compound Yiganling dripping pills and diseases, applied to medical preparations containing active ingredients, pharmaceutical formulas, unknown raw materials, etc. Health level and other issues, to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2005-12-21
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0027] Now with several groups of specific examples, the preparation method of the compound Yiganling dripping pills of the present invention will be further described.

[0028] [Group 1: Trials with a single substrate]

[0029] 1. Mixed drug raw materials: take g or kg as the unit, take 3 parts of Yiganling powder and 8 parts of Wurenol extract, mix well, and set aside;

[0030] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0031] 3. Proportion: take g or kg as the unit, by weight parts, mixed drug raw material: matrix = 1:1~1:9;

[0032] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Compound Yiganling Dropping Pills of different specifications.

[0033] [test results]

[0034] Experiment 1: In order to obs...

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PUM

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Abstract

The present invention discloses a Chinese medicine composition with the actions of boosting liver, enriching kidney, removing toxic material and dispelling dampness for curing the diseases of hypochondriac pain, reduced food intake, obdominal distention, aching lumbus, lack of strength and yellow urine, etc. due to deficiency of liver-yin and kidney-yin and noxious dampness. Said Chinese medicine composition can be made into compound Yiganling dripping pills, and is made up by using Chinese medicine Yiganling powder and Wurenchun extract as raw material and medicinal carrier as matrix through a certain preparation process.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the functions of nourishing the liver, nourishing the kidney, detoxifying and removing dampness, and is used for the treatment of hypochondriac pain, anorexia, abdominal distension, backache and fatigue, yellow urine and other diseases caused by liver and kidney yin deficiency and unclear damp toxin. The invention relates to an oral preparation of a pharmaceutical composition prepared from traditional Chinese medicine Yiganling powder (silymarin) and Wurenol extract as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 - Compound Yiganling Tablets prepared by the preparation method given in B-2380-97 is a kind of tablet that has the functions of nourishing the liver and nourishing the kidney, detoxifying and removing dampness, and is used for hypochondriac pain caused by liver and kidney yin deficiency and unclear damp toxin , Anorexia, abdominal ...

Claims

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Application Information

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Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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