Compound combination of Chinese traditional medicine in use for lowering viscosity of whole blood, thrombolysis and reducing blood fat

A compound traditional Chinese medicine and composition technology, applied in the field of medicine, can solve the problems of abnormal organ function, weak thrombectomy ability, and low specificity of curative effect, and achieve the effects of reducing whole blood viscosity, significant safety and improving therapeutic effect.

Inactive Publication Date: 2005-08-31
KUNMING SHENGHUO PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the following drugs are generally used in the treatment of this disease at home and abroad: such as anti-anginal drugs nitroglycerin, efodipine, nifedipine, etc.; blood lipid drugs niacin, phenoxy acids; antioxidant probucol, etc. Kinase (SK), urokinase (UK), statins, etc., but the above-mentioned drugs have serious adverse reactions, and long-term use or excessive doses will cause abnormal functions of other tissues and organs in the human body
Xuesaitong series of drugs for blood circulation disorders have been used clinically for many years, and the long-term blood index safety is better than the above products, but due to the wide clinical scope, the specificity of curative effect is not outstanding, and it is slightly inferior to statins in reducing blood viscosity. Thrombosis ability is also weak, therefore, it is urgent to develop a safe and efficient drug for reducing blood viscosity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Panax notoginseng saponins 60g Lumbrokinase 50g Tea polyphenols 100g

[0022] Safflower seed oil 240g Gelatin 220g Glycerin 90g

[0023] Ethylparaben 0.1g Distilled water 250g Cocoa bean pigment 50mg

[0024] The above raw and auxiliary materials are made into 1000 soft capsules

[0025] Preparation method: Mix Panax notoginseng saponins, lumbrokinase, tea polyphenols and safflower seed oil, grind and mix with a colloid mill for 30 minutes, release for later use; mix gelatin and distilled water, heat to dissolve at 40-50°C, heat up to 70°C ℃, add pigment and preservative, stir for 30 minutes, vacuumize at 0.08Mpa vacuum for 30 minutes, cool down to 40-50℃, keep warm for 2-4 hours, and set aside; pass the prepared medicine and glue through the soft capsule unit Press into soft capsules, dry, remove the waste pills, wash off the lubricating oil on the surface of the capsules with ethanol, dry, pack to obtain the finished product.

Embodiment 2

[0027] Panax notoginseng total saponins 60g lumbrokinase 40g peanut oil soybean oil 50g

[0028] Gelatin 150g Glycerin 60g Ethylparaben 0.06g Distilled water 180g

[0029] Lemon yellow pigment 50mg

[0030] The above raw and auxiliary materials are made into 1000 soft capsules

[0031] Preparation method: Mix Panax notoginseng saponins, lumbrokinase and peanut oil, grind and mix with a colloid mill for 30 minutes, release for later use; mix gelatin and distilled water, heat to dissolve at 40-50°C, heat up to 70°C, add pigments and preservatives , stirred for 30 minutes, evacuated for 30 minutes at a vacuum degree of 0.08Mpa, cooled to 40-50°C, kept warm for 2-4 hours, and set aside; the prepared medicinal solution and glue were pressed into soft capsules by a soft capsule unit, dried, The waste pills are removed, the lubricating oil on the surface of the capsules is washed away with ethanol, dried and packaged to obtain the finished product.

Embodiment 3

[0033] Panax notoginseng total saponins 100g tea polyphenols 100g refined oil 200g linolenic acid 100g

[0034] Gelatin 250g Glycerin 100g Ethylparaben 0.15g

[0035] Distilled water 300g Sunset yellow pigment 80mg

[0036] The above raw and auxiliary materials are made into 1000 soft capsules

[0037] Preparation method: mix Panax notoginseng saponins, tea polyphenols and refined oil, grind and mix with a colloid mill for 30 minutes, release for later use; mix gelatin and distilled water, heat to dissolve at 40-50°C, heat up to 70°C, add pigment and Preservatives, stirred for 30 minutes, evacuated at 0.08Mpa vacuum for 30 minutes, cooled to 40-50°C, kept warm for 2-4 hours, and set aside; the prepared liquid medicine and glue were pressed into soft capsules by a soft capsule machine, Drying, removing waste pills, washing with ethanol to remove lubricating oil on the surface of the capsules, drying, and packaging to obtain the finished product.

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PUM

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Abstract

A Chinese medicine for decreasing blood viscosity and blood fat and dissolving thrombus contains arasaponin, earthworm kinase and theapolyphenol.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a compound traditional Chinese medicine preparation for lowering whole blood viscosity, thrombolysis and lipid-lowering by using Panax notoginseng saponins, lumbrokinase, tea polyphenols and the like as raw materials and a preparation method thereof. Background technique [0002] Cardiovascular and cerebrovascular diseases are currently the most important disease that endangers human health, and have an increasing trend year by year, becoming the serious disease that ranks first in disability and death rates. With the continuous rise of living standards, now, not only in developed countries, but also in some industrialized countries and many developing countries, cardiovascular and cerebrovascular diseases have become the "first executioner" of human life. According to statistics, the incidence of cardiovascular diseases in my country The rate is increasing year by y...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K9/20A61K9/48A61K38/48A61P3/06A61P7/02A61P9/10
Inventor 蓝桂华陈蓬方松兰锋
Owner KUNMING SHENGHUO PHARMA GRP
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