Oral drop pills in use for treating diseases of bacterial infection and preparation method
A technology for bacterial infection and disease, applied in antibacterial drugs, respiratory diseases, and resistance to vector-borne diseases, etc., can solve problems that are not conducive to improving patients' ability to seek medical treatment, bioavailability of liver and intestine first-pass effect, and adverse overall health level. , to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and ensuring the quality of drugs
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[0027] Now with several groups of specific examples, the preparation method of Yanlixiao dripping pills of the present invention will be further described.
[0028] Group 1: Tests with a single matrix
[0029] 1. Preparation of the medicinal extract: Take an appropriate amount of clove leaves, add water and decoct twice, the first time is 1.5h, the second time is 1h, the decoction is combined, filtered, and the filtrate is concentrated under reduced pressure to a relative density of 1.25 (80°C) The clear paste is dried at 60°C to 80°C, crushed into fine powder, and obtained;
[0030] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;
[0031] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0032] ...
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