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Medicinal composition for regulating blood fat, prepn. method and use thereof

A technology for regulating blood lipids and compositions, applied in the field of pharmaceutical compositions and their preparation, to achieve the effects of scientific and precise drug compatibility, small dosage of drugs, and retention of active ingredients

Active Publication Date: 2005-05-25
CHENGDU DIAO JIUHONG PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

Among other disclosed compound Chinese medicines, there is no compound Chinese medicine with the same or similar composition as the raw materials of the composition of the present invention

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: the preparation of pharmaceutical composition capsule of the present invention:

[0036] Hawthorn 2000g Alisma 1500g Atractylodes macrocephala 1500g Red yeast rice 1000g

[0037] Add 6 times the amount of 80% ethanol to the above four medicinal materials, and reflux and extract three times, each time for 1.5 hours. Filtrate, recover ethanol from the filtrate to a relative density of 1.00-1.03 (60°C), concentrate under reduced pressure to a relative density of 1.20-1.25 (60°C), add 4-5 times the amount of water, let stand, centrifuge, and separate the precipitate. dry. The supernatant is passed through the pretreated macroporous resin column, washed with water until colorless, and then washed with 70% ethanol until colorless, the eluate is collected, the ethanol is recovered, concentrated into a thick paste, dried, and combined with the above dried centrifugal precipitate , pulverized, sieved, added an appropriate amount of micropowder silica gel, mixed e...

Embodiment 2

[0039] Embodiment 2 The content determination of the quality control index component of the pharmaceutical composition of the present invention:

[0040] Take the content of 10 capsules of this product, mix well, take 0.2g, accurately weigh, put in a 100ml Erlenmeyer flask, add 20ml of ether, ultrasonicate for 10 minutes (cold water bath), filter, wash the precipitate twice with ether, 20ml each time, the filtrates were combined, evaporated to dryness, and the residue was dissolved by adding absolute ethanol and transferred to a 10ml measuring flask, and diluted to the mark, as the test solution. Take another ursolic acid reference substance, add absolute ethanol to make a solution containing 0.3mg per 1ml, as the reference substance solution. Test according to thin-layer chromatography (Appendix VI B of Chinese Pharmacopoeia in 2000), draw 5 μl of the test solution, 5 μl and 10 μl of the reference solution, respectively cross points on the same silica gel G thin-layer plate, ...

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PUM

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Abstract

A Chinese medicine for treating hyperlipemia and fatty liver is prepared from haw, white atractylodes rhizome, alismatis rhizome and red koji. Its advantages are high curative effect and low toxic by-effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition and its preparation method and application, in particular to a pharmaceutical composition prepared from a traditional Chinese medicine compound as a raw material, its preparation method and application, and belongs to the field of traditional Chinese medicine. Background technique [0002] With the improvement of people's living standards and the aging population, the incidence of hyperlipidemia (mainly manifested as elevated serum cholesterol TC and triglyceride TG, and decreased high-density lipoprotein cholesterol HDL-C) has increased year by year. Hyperlipidemia caused by metabolic disorders has become an important pathogenic factor of common diseases such as fatty liver, coronary heart disease and atherosclerosis. [0003] Hyperlipidemia belongs to the category of "phlegm turbidity" and "blood stasis" in traditional Chinese medicine. A large number of long-term clinical practices have shown th...

Claims

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Application Information

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IPC IPC(8): A61P1/16A61P3/06
Inventor 李伯刚刘忠荣及元乔王若竹刘瑜付铁军邹文俊
Owner CHENGDU DIAO JIUHONG PHARMA FACTORY
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