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Hollow capsule of natural plant gum and its preparing process

A technology of hollow capsules and vegetable gums, applied in the direction of capsule transportation, etc., can solve the problems of temperature and humidity sensitivity, capsules are prone to brittleness, aggregation and deformation of gelatin capsules, etc. It achieves good stability, simple and easy production process, and is convenient for long-term use storage effect

Inactive Publication Date: 2005-04-20
ZHEJIANG YAOLIAN CAPSULES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Since gelatin is a material derived from animals, capsules made of gelatin are restricted and cannot be taken by people who believe in Islam and Judaism. They can only take tablets or inject medicines; Relatively sensitive to humidity, gelatin capsules will aggregate and deform under high temperature or high humidity conditions; under dry conditions, capsules tend to become brittle

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1, the proportioning of the glue solution of plant hollow capsule is as follows: pectin 16%-23%, chitosan 2.5%, carboxymethyl starch 0.6%, hydroxypropyl cellulose 0.6%, sodium lauryl sulfate 0.025%-0.026%, glycerin 0.169%-0.191%, and the balance is water.

[0015] Its production equipment is the same as the original production of hollow capsules with gelatin. The pectin is soaked and swollen with water first, put into the reaction pot for stirring and dissolving, add chitosan, carboxymethyl starch, hydroxypropyl cellulose and sodium lauryl sulfate, during which 85 ℃ of circulating water, dissolve in the reaction pot for 2.5 hours, filter the glue with a 120-mesh filter bag, store the glue in an insulated barrel, adjust the concentration of the glue, peel and remove air bubbles, and dip in the glue on the automatic glue dipping production line. Drying, cooling, demoulding, cutting, fitting, inspection, and packaging to form vegetable glue hollow capsules. Du...

Embodiment 2

[0017] Embodiment 2, pectin 18%; Carrageenan 6%; Chitosan 2.0%; Carboxymethyl starch 0.8%; Hydroxypropyl cellulose 0.8%; for water. Production method is with embodiment 1.

Embodiment 3

[0018] Embodiment 3, carrageenan 22%; chitosan 1.5%; carboxymethyl starch 1.0%; sodium lauryl sulfate 0.025%, glycerin 0.16%, and the balance is water. Its production method is with embodiment 1.

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PUM

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Abstract

Said invention relates to formula and preparation of plant hollow capsule for packaging powdered preparation, which is composed of 16-25 % of vegetable gelatin, 2.0-5.0 % of intensifier, 0.02-0.026 % of surface active agent, 0.15-0.20 % of moistening agent, the others is water. The said vegetable gelatin is one of or both of pectin and carrageenin, said intensifier is one kind or more than one kind of chitosan, carboxymethyl starch and hydroxyporpyl cellulose. Said surface active agent is sodium dodecyl sulfate. Said moistening agent is glycerol. Said plant hollow capsule has good stability, stored for long time and also can be produced by utilizing the equipment used in producing capsule from geltin.

Description

【Technical field】 [0001] The invention relates to the field of pharmaceutical preparations, in particular to a hollow capsule for packaging powder preparations and a production process thereof. 【Background technique】 [0002] At present, the application of hard hollow capsules as a drug carrier is very common. Hard hollow capsules are generally made of gelatin and water. According to the production season and user needs, preservatives and food coloring can be added. The production process is as follows: gelatin is soaked in water, expanded, stirred and dissolved in a reaction pot, and the temperature of the reaction pot is kept at 60°C-75°C. After dissolution, the gelatin is filtered, the concentration of the gelatin is adjusted, stored and kept warm, peeled to remove air bubbles, On the automatic glue dipping production line, it goes through glue dipping, drying, cooling, demoulding, cutting, fitting, inspection, and packaging. [0003] Since gelatin is a material derived ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48
Inventor 钱俊青章有献
Owner ZHEJIANG YAOLIAN CAPSULES
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