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Medicinal composition for treating ulcerative colitis and its preparing method

A technology of ulcerative colitis and composition, applied in the field of traditional Chinese medicine, can solve the problems of lack of treatment methods and no specific medicines yet, and achieve remarkable clinical curative effect, definite clinical curative effect, and safe use

Inactive Publication Date: 2006-10-04
GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective treatment for this disease clinically, and no specific medicine has appeared yet.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Prescription: 7 parts by weight of Pulsatilla chinensis, 5 parts by weight of bark bark, 5 parts by weight of Cortex Phellodendri, 2 parts by weight of Coptis chinensis, 3 parts by weight of comfrey, 4 parts by weight of agrimony, 3 parts by weight of myrobalan, 3 parts by weight of madder, 4 parts by weight of white root , Qingdai 4 parts by weight.

[0043] (1) Take 7 parts of Pulsatilla chinensis, 5 parts of Qinpi, 4 parts of Agrimony, and 3 parts of Myrobalan, decoct and extract twice with water, each time for 1 to 2 hours, filter the water extracts, and combine them. The filtrate was concentrated under reduced pressure to a relative density of 1.03-1.13 (60°C). After the concentrate was allowed to cool, 95% (V / V) ethanol was added to make the alcohol content 70% (V / V). Let stand overnight and filter out the precipitate. The alcohol precipitation solution was concentrated under reduced pressure into a concentrated solution for later use.

[0044] (2) Take 2 parts o...

Embodiment 2

[0051] Prescription: 5 parts by weight of Pulsatilla chinensis, 6 parts by weight of bark bark, 4 parts by weight of Cortex Phellodendri, 1 part by weight of Coptis chinensis, 5 parts by weight of comfrey, 4 parts by weight of agrimony, 2 parts by weight of myrobalan, 3 parts by weight of madder, 5 parts by weight of white root , Qingdai 5 parts by weight.

[0052] (1) Take 5 parts of Pulsatilla chinensis, 6 parts of Qinpi, 4 parts of Agrimony, and 2 parts of Myrobalan, decoct and extract twice with water, each time for 1 to 2 hours, filter the water extract, and combine. The filtrate was concentrated under reduced pressure to a relative density of 1.03-1.13 (60°C). After the concentrate was allowed to cool, 95% (V / V) ethanol was added to make the alcohol content 70% (V / V). Let stand overnight and filter out the precipitate. The alcohol precipitation solution was concentrated under reduced pressure into a concentrated solution for later use.

[0053] (2) Take 1 part of Coptid...

Embodiment 3

[0060] Prescription: 3 parts by weight of Pulsatilla chinensis, 4 parts by weight of bark bark, 4 parts by weight of Cortex Phellodendri, 3 parts by weight of Coptis chinensis, 4 parts by weight of comfrey, 4 parts by weight of agrimony, 3 parts by weight of myrobalan, 2 parts by weight of madder, 6 parts by weight of white root , Qingdai 5 parts by weight.

[0061] (1) Take 3 parts of Pulsatilla chinensis, 4 parts of Qinpi, 4 parts of Agrimony, and 3 parts of Myrobalan, decoct and extract twice with water, each time for 1 to 2 hours, filter the water extract, and combine. The filtrate was concentrated under reduced pressure to a relative density of 1.03-1.13 (60°C). After the concentrate was allowed to cool, 95% (V / V) ethanol was added to make the alcohol content 70% (V / V). Let stand overnight and filter out the precipitate. The alcohol precipitation solution was concentrated under reduced pressure into a concentrated solution for later use.

[0062] (2) Take 3 parts of Copt...

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Abstract

The medicine composition for treating ulcerative colitis has the active components from the ten kinds of Chinese medicinal materials, including pulsatillae root, ash bark, phellodendron bark, Chinese goldthread, gromwell, etc. The enema with the medicine composition as active components may be used in treating ulcerative colitis. The medicine composition has strict recipe, obvious treating effect and low cost, and it is prepared into biological adhering preparation for enema capable of acting on the disease site directly and prolonging the medicine releasing period.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating ulcerative colitis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Ulcerative colitis is a worldwide problem in medicine at present. Its etiology is unknown, and there is no conclusion so far. Once it occurs, the course of the disease is lingering and protracted, and it often presents attacks-relieving repeated and alternating changes, which is extremely difficult to cure. The incidence rate of ulcerative colitis is 5-12 / 100,000. It is a disease with a high incidence rate. It can occur in all age groups, most of which are 20-40 years old. There is no significant difference in the incidence rate between men and women. In the treatment of ulcerative colitis, Western medicine focuses on eliminating symptoms, controlling attacks, and reducing recurrence. Commonly used drugs are SASP, hormones, and immunosuppressants, b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61K36/756A61K36/74A61K36/73A61K36/718A61K36/71A61K36/30A61K36/19A61K36/70A61K36/315A61K36/185A61P1/04
Inventor 刘萍罗庆良马凤彩张再厚李外陈利平胡景华古今杨洁
Owner GENERAL HOSPITAL OF PLA
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