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Medicine for treating Parkinson's disease and its preparing process

A technology for Parkinson's disease and processing methods, applied in drug combinations, pharmaceutical formulas, nervous system diseases, etc., can solve problems such as high prices, unsatisfactory curative effects, and adverse reactions

Inactive Publication Date: 2005-12-28
JINAN CENTER HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of treatment can easily aggravate or cause dementia
Moreover, there is no breakthrough in the current treatment of PD drugs. Most anti-PD drugs still need to be imported or produced by joint ventures. They are expensive, have unsatisfactory curative effects, and have many side effects and adverse reactions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] In the following examples, when cat beans are used as raw materials, the cat beans and other raw materials are crushed to 100-120 mesh, and they are conventionally made into capsules or pills.

[0009] When the crude cat pea extract is used as the raw material, the crude cat pea extract is obtained by the following method: mash the cat pea seeds, soak them in acetic acid and dilute ethanol solution for 18-24 hours, and use vacuum or corresponding The equipment is concentrated under reduced pressure, and the concentrated liquid is dried at 50-60°C to obtain the crude cat bean extract as the solid. The other raw materials are crushed to 100-120 mesh, mixed with the crude cat bean extract, and then made into capsules or pills according to conventional methods.

[0010] When the cat bean extract is used as the raw material, the above-mentioned concentrated liquid is precipitated and filtered again. Add 24 times water and a small amount of 0.1% vitamin C and activated carbon to ...

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PUM

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Abstract

The invention relates to a medicine for treating Parkinson's disease and a processing method thereof. The raw materials and their weight ratios are cat bean or its extract 2-15, Shouwu 6-13, Yangjinhua 0.2-0.5, ginseng 0.5-11.5, Panax notoginseng 2-6, Angelica 2-9, Salvia miltiorrhiza 3-11.5, Gynostemma 2-11.5, Eucommia charcoal 3-11.5, Epimedium 3-9, Bombyx mori 2-11.5, Magnolia officinalis 2-9. During processing, crush the cat bean seeds, soak them in acetic acid and dilute ethanol solution for 18-24 hours, use vacuum or corresponding equipment to concentrate the infusion under reduced pressure, and dry the concentrate at 50-60°C to obtain the cat bean extract . After the cat bean or its extract is pulverized, it can be made into dosage forms such as capsules and pills according to conventional methods. The present invention corrects the method of increasing DA content and reducing Ach content to achieve abnormal physiological balance in the traditional treatment of PD in the past, and increases DA and Ach at the same time to reach or tend to the normal physiological balance required by human health. In a word, the present invention solves the balance problem of neurotransmitters, and can also protect the nerves against oxidation, so as to achieve the purpose of effectively treating Parkinson's disease. In addition, various components in the present invention have low cost and little toxic and side effects.

Description

Technical field [0001] The present invention is a medicine for treating Parkinson's disease and its processing method. Background technique [0002] Nowadays, with the aging of human population, the incidence and prevalence of senile diseases such as Parkinson's disease (PD) are increasing year by year, which seriously affects work and daily life. The disease has become one of the main diseases that cause disability and death in the elderly. One. The main pathological changes of Parkinson's disease are the degeneration of dopaminergic neurons in the substantia nigra compact area, the DA content of the striatum is significantly reduced, and the oxidative stress is enhanced, mitochondrial dysfunction, excitotoxicity, and calcium cells are produced. Toxic effects and abnormal immune function are important factors for PD cell degeneration. In short, Parkinson's disease is mainly due to a large decrease in DA in the brain, while the ACh in the brain of the elderly is already insuffici...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P25/16
Inventor 刘希汉戴岗梅
Owner JINAN CENTER HOSPITAL
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