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Skin-infiltrating film of Chinese traditional medicine for treating paralysis resulting from central nerve trauma and its preparation method

A technology of central nervous system and traditional Chinese medicine, which can be used in pharmaceutical formulations, nervous system diseases, medical preparations containing active ingredients, etc., and can solve problems such as no treatment.

Inactive Publication Date: 2005-07-06
詹军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the damage to the central nervous system can be treated, its dominance and integration of the muscles of the limbs can be restored, and the paralyzed limbs can be restored to activity. However, there is currently no effective drug for this disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Embodiment 1: The proportioning of the prescription is: Rhizoma Chuanxiong 40g, Guizhi 40g, Angelica sinensis 10g, Salvia miltiorrhiza 9.97g, musk 0.03g.

[0009] Preparation method: Grind Chuanxiong, Guizhi, Angelica, and add 2500ml of water to boil until 500ml, take out the liquid medicine, and do the same three times as above to obtain a total of 1500ml of liquid medicine, concentrate to 500ml, add the adjusted film-forming material carboxymethyl Sodium cellulose base 25g, stir evenly, in addition, musk is dissolved in 10ml of 95° ethanol, fully stirred with the drug solution, and made into a film tape with a width of about 12cm and a thickness of about 1mm on a film coating machine. After the content is determined Scratches divided into grids, each grid area is about 1cm 2 , each box contains about 25mg (±10%) of crude drug, sterilized by ultraviolet light for 30 minutes, sealed and packaged in a polyethylene film bag.

Embodiment 2

[0010] Embodiment two: the proportioning of prescription is: Chuanxiong 25g, cassia twig 25g, angelica 25g, salvia miltiorrhiza 24.94g, musk 0.06g.

[0011] In the preparation method, 30 g of polyvinyl alcohol was selected as the film-forming material, and the rest were the same as in Example 1.

Embodiment 3

[0012] Embodiment 3: The weight ratio of the prescription is: Rhizoma Chuanxiong 10g, Guizhi 10g, Angelica sinensis 40g, Salvia miltiorrhiza 39.9g, musk 0.1g.

[0013] In the preparation method, 30 g of methyl polyethylene was selected as the film-forming material, and the rest were the same as in Example 1.

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PUM

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Abstract

The present invention is Chinese medicine transdermal film preparation for treating paralysis caused by damage in central nerve. The recipe consists of Chuanxiong rhizome, cassia twig, angelica, redsage and musk; and the preparation process includes material sorting, washing, stoving, crushing, decoction, concentration, preparing film material, filming, content measurement and packing. The present invention has special treating effect on apoplexy and hemiplegia caused by cerebral haemorrhage, cerebral thrombosis, injury of brain and spinal cord via sticking the film preparation onto relevant acupoints and skin parts. The transdermal treatment of the present invention has fast medicine absorption, fast acting, lasting action and no irritation to skin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine transdermal film agent for treating paralysis after central nervous injury caused by cerebral hemorrhage, cerebral infarction, cerebral thrombosis, traumatic brain and spinal cord and other causes and a preparation method thereof. Background technique [0002] Cerebral hemorrhage, cerebral infarction, cerebral thrombosis, brain and spinal cord trauma and other diseases can all cause damage to the central nervous system such as the brain cells and spinal cord of the patient, making the patient's limbs paralyzed due to the loss of central nervous system control. In the early stage of paralysis, the muscles of the limbs show soft paralysis without any tension. In the later stage of paralysis, muscle spasms will appear due to excessive muscle tension, which is manifested as hard paralysis. This is because the limb muscles lose the innervation and Emerged from integration and coordination. If the dama...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K35/55A61K47/38A61M37/00A61P7/02A61P9/10A61P25/00
Inventor 詹闯詹军
Owner 詹军
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