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Polysaccharide compound separated from frankincense or vinegar frankincense as well as preparation method and application of polysaccharide compound

A technology of polysaccharides and compounds, applied in the field of polysaccharide compounds and their preparation, can solve the problems of unreported composition and application of boswellia polysaccharides in vinegar, few reports of boswellia polysaccharides, etc., achieve good economic value and social benefits, and enhance immunity force effect

Pending Publication Date: 2022-06-07
SHENYANG PHARMA UNIVERSITY
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Problems solved by technology

[0005] However, there are few reports about boswellia polysaccharides at present, especially the composition and application of vinegar boswellia polysaccharides have not been reported

Method used

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  • Polysaccharide compound separated from frankincense or vinegar frankincense as well as preparation method and application of polysaccharide compound
  • Polysaccharide compound separated from frankincense or vinegar frankincense as well as preparation method and application of polysaccharide compound
  • Polysaccharide compound separated from frankincense or vinegar frankincense as well as preparation method and application of polysaccharide compound

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preparation example Construction

[0035] (1) Preparation of crude polysaccharide: take the resin exuded from the bark of Boswellia carterii Birdw. bark (purchased from Hebei Meikang Pharmaceutical Co., Ltd. (Anguo), which is Ethiopian frankincense, or the resin exuded from the bark of Boswellia carterii Birdw. , according to the provisions of the "Chinese Pharmacopoeia" 2020 edition under a frankincense item, use 5g of rice vinegar for every 100g of processed products. Take the frankincense and break it into small pieces, heat it in a pot over medium heat, and stir fry until the surface is slightly melted into a spherical shape. When there is smoke coming out, spray the corresponding amount of rice vinegar, and stir-fry while spraying to make the heating evenly and fully contact with the rice vinegar. When frying until the surface of the frankincense has a glossy luster, take it out quickly. Every 100g of raw frankincense obtains 98.7g of frankincense made from vinegar Add 8 times the amount of water and heat u...

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Abstract

The invention belongs to the field of medicines, and particularly relates to a polysaccharide compound separated from frankincense or vinegar frankincense as well as a preparation method and application of the polysaccharide compound. According to the method, crude mastic and vinegar mastic polysaccharides are obtained by utilizing water extraction, alcohol precipitation and Sevage deproteinization methods. The method comprises the following steps: firstly, extracting crude polysaccharide by using ethanol, then carrying out column separation on the crude polysaccharide by using DEAE-52 cellulose, then carrying out subdivision by using G-50 and G-100 gel, respectively separating from frankincense and vinegar frankincense to obtain two single polysaccharides, and analyzing the monosaccharide composition, molecular weight and structure of the single polysaccharides to determine the chemical structures of the four single polysaccharides. In pharmacodynamic research, a Raw264.7 cell experiment shows that the single polysaccharide disclosed by the invention has certain immunocompetence, and a rat cold coagulation and blood stasis experiment shows that the polysaccharide monomer disclosed by the invention has certain blood stasis resisting activity.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a polysaccharide compound separated from frankincense or frankincense vinegar and a preparation method and application thereof. Background technique [0002] Frankincense is the resin exuded from the bark of the olive plant Boswellia carterii Birdw. and Boswelliabhaw-dajiana Birdw. of the same genus. It is divided into Somali Frankincense and Ethiopian Frankincense. Frankincense is warm in nature, pungent and bitter in taste, and has the functions of promoting blood circulation and relieving pain, reducing swelling and promoting muscle growth. From the perspective of traditional Chinese medicine, frankincense is mainly used to treat blood stasis syndrome. "Blood stasis syndrome" is the name of a syndrome in traditional Chinese medicine. Refers to the internal resistance of blood stasis, mainly manifested by pain, mass, bleeding, purple tongue, and astringent pulse. Blood st...

Claims

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Application Information

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IPC IPC(8): C08B37/00A61P7/02A61P1/04A61P1/06A61P15/00A61P37/02
CPCC08B37/0003C08B37/006A61P7/02A61P1/04A61P1/06A61P15/00A61P37/02Y02A50/30
Inventor 刘晓秋潘英妮王冬梅郭静妍任舒蒙
Owner SHENYANG PHARMA UNIVERSITY
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