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Sanqi dampness-eliminating formula and application thereof

A technology of dampness-removing and dampness-reducing formulas, applied in Sanqi Qushi-reducing formulas and its application fields, which can solve problems such as not showing ideal therapeutic effects

Active Publication Date: 2022-05-31
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sanqi Oral Liquid is mainly used to treat chronic nephritis clinically, and has a better curative effect on patients with chronic nephritis clinically manifested as a small amount of proteinuria; Patients with kidney disease, clinically did not show ideal therapeutic effect

Method used

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  • Sanqi dampness-eliminating formula and application thereof
  • Sanqi dampness-eliminating formula and application thereof
  • Sanqi dampness-eliminating formula and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The Sanqi Qushi traditional Chinese medicine decoction of this embodiment consists of the following raw materials in parts by mass: 50 g of astragalus, 10 g of notoginseng, 15 g of curcuma, 15 g of red peony, 20 g of Atractylodes macrocephala, 20 g of cicadae, and 30 g of Smilax smilax.

[0042] Its preparation method comprises the following steps:

[0043]Weigh the crude drug according to the proportion, add 10 times the weight of water, heat to boil and keep boiling for 1h, filter to obtain the first filter residue and the first filtrate, then add water 8 times the weight of the first filter residue, heat to boil and keep Slightly boil for 1h, filter to obtain the second filter residue and the second filtrate, and combine the first filtrate and the second filtrate to obtain the obtained product.

[0044] The Chinese medicine decoction prepared in this embodiment is a dosage, and the dosage of a dosage is 119.76 (about 120) mL.

[0045] In addition, in order to obtain...

Embodiment 2

[0047] The Sanqi Qushi traditional Chinese medicine decoction of this embodiment is composed of the following raw materials in parts by mass: 30 g of astragalus, 5 g of notoginseng, 15 g of curcuma, 15 g of red peony, 15 g of Atractylodes macrocephala, 10 g of cicadae, and 30 g of Smilax smilax.

[0048] Its preparation method comprises the following steps:

[0049] Weigh the crude drug according to the proportion, add 10 times the weight of water, heat to boil and keep boiling for 1h, filter to obtain the first filter residue and the first filtrate, then add water 8 times the weight of the first filter residue, heat to boil and keep Slightly boil for 1h, filter to obtain the second filter residue and the second filtrate, and combine the first filtrate and the second filtrate to obtain the obtained product.

[0050] The traditional Chinese medicine decoction that present embodiment makes is one dosage, and one dosage is 200mL.

[0051] In addition, in order to obtain the trad...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a radix astragali, radix notoginseng and radix astragali dampness-clearing formula and application thereof, and the radix astragali, radix notoginseng and radix astragali dampness-clearing formula comprises the following raw material medicines in parts by weight: 15-60 parts of radix astragali, 5-10 parts of radix notoginseng, 5-15 parts of rhizoma curcumae, 5-15 parts of radix paeoniae rubra, 5-20 parts of rhizoma atractylodis macrocephalae, 10-20 parts of cordyceps sobolifera and 10-30 parts of rhizoma smilacis glabrae. The invention also provides application of the Sanqi dampness-eliminating formula. Clinical tests show that the Sanqi dampness-clearing prescription can significantly improve the remission rate of a patient with membranous nephropathy, and when the Sanqi dampness-clearing prescription is combined with an immunosuppressive agent to treat membranous nephropathy, the curative effect is obvious, and the safety is good. Animal experiments show that the Sanqi dampness-clearing formula can improve general conditions such as appetite, body weight, activity, mental state, hair, hair color, urination and defecation of doxorubicin-induced nephrotic syndrome rats; the urine protein level of rats can be reduced to a certain extent; the pathological state of the rat kidney tissue is improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a Sanqi Qushi formula and its application. Background technique [0002] Membranous nephropathy (membranous nephropathy, MN), also known as membranous glomerulonephritis, is a common cause of nephrotic syndrome in adults. Syndrome, hypertension, and edema are the main manifestations, and thrombosis is its common complication. Pathologically, the glomerular capillary basement membrane is uniformly thickened with diffuse subepithelial immune complex deposition. Membranous nephropathy can be relieved by general treatment, drug treatment and other methods. [0003] At present, the four most commonly used drug regimens in Western medicine for membranous nephropathy are: ① alkylating agents (chlorambucil, cyclophosphamide) + glucocorticoids; ② calcineurin inhibitors [CNIs] (tacrolimus , cyclosporine A) + glucocorticoid; ③ mycophenolate mofetil (Mycophenolate ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P13/12A61K35/64
CPCA61K36/481A61K36/258A61K36/9066A61K36/71A61K36/65A61K36/284A61K36/068A61K35/64A61K36/90A61K36/896A61P13/12A61K2300/00Y02A50/30
Inventor 包崑黎创王丽娟洪晓帆李苹袁怡刘博杨霓芝张清华梁星苏卓伟左琪马伟忠王荣荣江莎
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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