Preparation method and application of alkanet root extract with stable color

Abstract

The invention discloses a preparation method of a lithospermum root extract with stable color, which comprises the following steps: mixing lithospermum roots and an ethanol solution with the volume fraction of 50% according to the solid-liquid ratio of 1g: 30mL, and carrying out high-pressure treatment and filtration to obtain a crude lithospermum root extract; uniformly mixing petroleum ether, ethyl acetate, methanol and water according to a volume ratio of (5-7): (3-5): (4-6): (4-6), and standing for layering to prepare a stationary phase and a mobile phase; respectively pumping the stationary phase, the mobile phase and the radix arnebiae crude extract into a high-speed counter-current chromatograph to obtain a high-purity radix arnebiae extract; preparing the high-purity alkanet root extract into alkanet root extract freeze-dried powder; and mixing the freeze-dried powder of the alkanet root extract with octyldodecanol myristate to obtain the alkanet root extract for cosmetics. The preparation method disclosed by the invention has the characteristics of simplifying steps and saving time, and the obtained extract has the characteristics of lasting and stable color, higher active matter purity and better anti-aging effect.

Description

technical field [0001] The invention relates to a comfrey root extract, in particular to a preparation method and application of a color-stable comfrey root extract. Background technique [0002] Comfrey (Lithospermum erythrorhizon Sieb. et Zucc.) is a perennial herb of the family Boraginaceae, and its dried root is used as medicine. The botanical name of comfrey was first recorded in "Shan Hai Jing·Xishan Jing", and the recorded name was Chicao, and its use was dyeing; as a traditional Chinese medicine, comfrey was first recorded in "Shen Nong's Materia Medica", which is the middle grade among the three grades; "Materia Medica "Compendium" records: Zicao "cures plaque and pox, promotes blood and cools blood, and benefits large intestine." It tastes bitter, salty, and cold, and returns to the liver meridian. Efficacy: Indications for the treatment of blood heat and toxin, impermeable leprosy, purple and black spotted plague, water and fire injury, damp epidemic, epidemic ul...

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Problems solved by technology

[0004] The commonly used extraction methods of naphthoquinone pigments are mostly the traditional reflux method, microwave method, percolation method, cold soaking method and other extraction methods, which generally have the disadvantages of cumbersome operation steps, long extraction time, high temperature, and low extraction rate. Extraction with microwave and microwave method will lead to the destruction of the total naphthoquinone components of Burgeon at high temperature, while the percolation and cold soaking methods have the problems of low extraction rate of naphthoquinone components, long time-consuming, large amount of solvent, and low solvent recovery rate.

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