A kind of high-resolution oct imaging device and imaging method thereof

An imaging device and high-resolution technology, applied in the field of optical imaging, can solve problems such as single measurement performance, small imaging field of view, and slow acquisition speed, and achieve the effects of improving sensitivity, high recovery efficiency, and improving receiving efficiency

Active Publication Date: 2022-05-17
PEKING UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In order to solve the problems of single measurement performance, slow acquisition speed, small imaging field of view and low resolution of existing OCT measuring instruments in the prior art, the present invention proposes a high-resolution OCT imaging device and its imaging method

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  • A kind of high-resolution oct imaging device and imaging method thereof
  • A kind of high-resolution oct imaging device and imaging method thereof
  • A kind of high-resolution oct imaging device and imaging method thereof

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Embodiment 1

[0053] Such as figure 2 As shown, in this embodiment, the sample is the outer skin, cerebral cortex, or cornea, etc., and there is no lens-like medium between the sample to be imaged and the imaging lens, so the imaging lens adopts a focusing imaging lens. In this embodiment, the first and second corner reflectors are used to divide a non-diffraction beam output by the light field modulation module into three non-diffraction beams, and the optical transmission path is changed by the first and second reflectors, respectively transmitting To the first to third sample arm branches; according to the interference signals of each sample arm branch, splicing and forming OCT images with high resolution and large field of view. The beam irradiated on the sample by the three-way sample arm branch is reflected by the sample, returns to each sample arm branch, and finally returns to the collimator. The efficiency is theoretically 100% when the device loss is ignored.

Embodiment 2

[0055] Such as Figure 4 As shown, in this embodiment, the sample is the eye, and the first and second corner reflectors are used to divide a non-diffracting beam output by the light field modulation module into three non-diffracting beams, and the first and second reflectors The mirror changes the transmission path of the optical path and transmits them to the first to third sample arm branches respectively; among the three sample arm branches, the first and third sample arm branches are the optical path of the posterior segment of the eye, and the second sample arm branch is the front Light-section path; when imaging the posterior segment of the eye, there is a lens-like medium between the sample and the imaging lens, so the imaging lens of the optical path of the posterior segment of the eye uses a 4F imaging lens. When imaging the anterior segment, there is no similarity between the sample and the imaging lens. The medium of the lens function, so the imaging lens of the an...

Embodiment 3

[0058] Such as Image 6 As shown, in this embodiment, the sample is the outer skin, cerebral cortex, or cornea, etc., and there is no lens-like medium between the sample to be imaged and the imaging lens, so the imaging lens adopts a focusing imaging lens. In this embodiment, a polarization beam splitter and a third angle reflector are used to divide the light beam into three, and the light field adjustment mode includes the first and second light field adjustment modes; the Gaussian beam emitted from the collimator to the polarization splitter The polarizing beam splitter is divided into two parts by the polarizing beam splitter, the P polarized light is transmitted, and the S polarized light is reflected; the reflected S polarized light passes through the third mirror and the second half-wave plate in turn, and after passing through the second light field adjustment module, the Gaussian The light beam becomes a non-diffracting beam, and then the non-diffracting beam is sent ...

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Abstract

The invention discloses a high-resolution OCT imaging device and an imaging method thereof. The present invention uses a corner reflector to split the light, and compared with the traditional method of splitting the light beam with the beam splitter, the recovery efficiency of the light beam is higher, close to 100%, which is of great value for improving the signal-to-noise ratio and sensitivity of the OCT system; the light field The modulation module turns the Gaussian beam into a non-diffracting beam, which can greatly improve the imaging depth of field of the OCT system and greatly improve the lateral resolution at the out-of-focus position; the high transmittance of the eye can play a better role in non-diffraction than high-scattering tissues. The advantage of the long focal depth of the beam; it can achieve 2-3 times the imaging field of view, and the simultaneous imaging of multiple sample arm branches can greatly reduce the field curvature and distortion caused by the large field of view, improve image quality, reduce the impact of aberrations, and improve resolution Higher; the use of corner reflectors with non-diffracting beams can solve the problem of lateral resolution degradation caused by the destruction of the Gaussian beam light field structure by the corner reflectors.

Description

technical field [0001] The invention relates to the technical field of optical imaging, in particular to a high-resolution OCT imaging device and an imaging method thereof. Background technique [0002] Optical coherence tomography (OCT) technology is based on the principle of low-coherence light interference, which can image human tissues in real time, non-destructively, and dynamically with high resolution. Capable of imaging subcutaneous microcirculation. It has proven to be an important tool in the detection and study of diseases of the skin, blood vessels and even the eyes. Driven by clinical need, OCT technology has rapidly moved into the clinic and is now considered the standard imaging technique in cardiovascular and ophthalmic care. In order to gain a deeper understanding of the pathological development process, it is necessary to obtain OCT structural information and even blood flow information with higher resolution, larger imaging field of view, and deeper imag...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B3/10
Inventor 任秋实胡毅成黄智宇周传清
Owner PEKING UNIV
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