Instant mouth wash powder
A gouache, instant technology, used in oral care, medical science, dentistry, etc., can solve problems such as destroying the balance of oral flora, and achieve the effect of inhibiting the growth of harmful bacteria, promoting secretion, and promoting oral health.
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preparation example Construction
[0024] (2) the preparation method of the instant mouthwash powder of this program is as follows:
[0025] S1: Preparation of antibacterial pre-preparation:
[0026] Mix acetic acid, sodium acetate and water for high-temperature prefabrication according to the formula, place it in a reaction kettle at 125-150°C (called prefabrication temperature), and keep warm for 0.5-2 hours after dissolution is complete (called holding time) , stirring and cooling to room temperature (about 20° C.) and filtering to take the solid phase to obtain a crystalline mixture. The crystals obtained by stirring and cooling are fine, and the water content of the crystalline mixture is controlled <5%; Get an antimicrobial prep.
[0027] S2: Preparation of antibacterial agent:
[0028] Mix the antibacterial pre-preparation, the sodium chloride of the formulated amount and the xylitol of the formulated amount to obtain the antibacterial agent.
[0029] S3: Preparation of finished powder
[0030] The ant...
experiment example 1
[0052] Experimental example 1: instant effect experiment of mouthwash powder
[0053] Get the mouthwash powder 10g of embodiment and comparative example, measure the time that it dissolves in 100ml water under the condition of 17 ℃, and after dissolving, measure the pH value of mouthwash, the instant gargle of each embodiment and comparative example The saliva powder was repeatedly tested 3 times, and the experimental results are shown in Table 2.
[0054] Table 2: Solubility properties and pH measurement results
[0055]
[0056] It can be seen from the experimental results that the prefabrication of sodium diacetate can promote the solubility of mouthwash powder, and the type of acidity stabilizer will also affect the solubility of mouthwash powder. Among them, the effect of using sodium carbonate is the best, hydrogen carbonate Sodium came next, and sodium acetate was the least effective.
experiment example 2
[0057] Experimental Example 2: Evaluation of User Effects
[0058] Randomly select 20 subjects to evaluate the effect of the mouthwash of this program. The experimental group (15 subjects, including 8 female subjects, 7 male subjects, and the average age of all subjects was 42 years old) among the subjects used the instant mouthwash powder of Example 1 of the technical solution. When using, dissolve 3g of instant mouthwash powder in 50ml of water until completely dissolved to obtain mouthwash. Gargle for 30 seconds, once a day in the morning and evening, use 20ml each time, and use it now. The subjects were also asked to brush their teeth once a day in the morning and evening (using ordinary toothpaste, which does not contain fluoride, pharmaceutical ingredients, probiotics or lysozyme, etc.), for 2 minutes each time. The control group (5 subjects, including 2 female subjects and 3 male subjects, with an average age of 36 years old) among the subjects did not use the instant...
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