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Cosmetic composition for skin improvement comprising green barley extract

A technology for cosmetic compositions and extracts, which can be applied to cosmetics, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as difficult to expect improvement in skin function, negligible effects, and limit usage, and achieve excellent skin barrier enhancement. , Excellent skin moisturizing, high utilization effect

Pending Publication Date: 2022-01-25
AMI COSMETIC CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the amount of these materials used when applied to the skin is limited due to safety issues such as irritation, erythema, redness, etc., and the effect of improving skin function is hardly expected due to insignificant effects

Method used

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  • Cosmetic composition for skin improvement comprising green barley extract
  • Cosmetic composition for skin improvement comprising green barley extract
  • Cosmetic composition for skin improvement comprising green barley extract

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0090] Preparation example 1. Preparation of samples such as green barley extract

[0091] 1-1. Preparation of green wheat extract by seedling cultivation machine (cultivation for two weeks)

[0092]In a house made of glass or plastic, there is provided a plurality of trays with small holes through which the roots of the seedlings can descend, under each of these trays, and consisting of a waterway that circulates water or a culture solution Culture plates and stacking tables (supporting tables) that can be stacked into multiple layers. Next, a culture solution circulator that circulates water or culture solution on the above-mentioned culture plate is provided; a water tank that stores water or culture solution supplied to the above-mentioned culture plate by the above-mentioned culture solution circulator; water is delivered from the above-mentioned water tank to the above-mentioned culture plate Or the first delivery pipe of the culture solution; and the second deliver...

preparation example 2

[0101] Preparation example 2. Preparation according to saponin during cultivation

[0102] As saponin used in the experiment, 10 mg of saponin purchased from EXTRASYNTHESE was dissolved in autoclaved distilled water, filtered through a 0.2 μM syringe filter, diluted with cell culture and treated to cells.

[0103] Saponin HPLC Analysis Conditions

[0104] -Column: C18

[0105] -Column Temperature: 30°C

[0106] -Injection Volume: 5μL

[0107] -Flow rate: 1.0mL / min

[0108] -Mobile phase: A: (5% acetic acid in water) 80%

[0109] D: Methanol 20%

[0110] - Gradient: None. From 0 minutes A 80%, D 20%

[0111] -Detector: UV 270nm

[0112] According to the analysis results, it was confirmed that the saponin content of the green wheat extract cultivated according to the above-mentioned Preparation Example 1 was higher ( figure 2 ).

preparation example 3

[0113] Preparation example 3. Preparation of saponarin, luteolin and apigenin

[0114] The green wheat extract prepared in Preparation Example 1 above was prepared to 5,000 ppm and used for analysis. A standard foam mixture was prepared to 1,000 ppm using a MeOH / pyridine mixed solvent, and the above standard foam mixture was diluted to 0.5-100 ppm and used for analysis.

[0115] HPLC conditions

[0116] - Instrument: Agilent Technologies 6410 triple quadrupole (LC-MS / MS)

[0117] -Column: Chromasil C18 (3.0mm×150mm, 3.0μm)

[0118] - Solvents: A; 0.1% formic acid in water, B; 0.1% formic acid in acetonitrile

[0119] -Flow rate: 0.4mL / min

[0120] -Injection volume: 5μL

[0121] -gradient:

[0122] - time (minutes) B％ 1 0 5 2 30 100 3 32 100

[0123] MS conditions

[0124] -Ionization Mode: ESI, scan mode

[0125] -Gas temp. (°C): 350

[0126] -Capillary volt. (V): 4000

[0127] - Atomizer (psig): 40

[0128] - Cracking volta...

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Abstract

Provided is a cosmetic composition for skin improvement including a green barley extract.

Description

technical field [0001] The present invention relates to a skin improving cosmetic composition containing green barley extract. Background technique [0002] The skin is a membrane that covers the outside of the body, and performs various physiological functions to protect the body from environmental factors such as various external stimuli, obstacles, and dryness, thereby protecting and regulating internal organs and other internal organs. [0003] However, as the age of the skin increases, the physiological function of the living body decreases, the secretion of various hormones that regulate metabolism decreases, and the function and cell activity of immune cells decrease. In addition, the appearance or function of the skin changes due to repeated exposure to light or heat, resulting in an increase in free radicals and active harmful oxygen, etc. Excessive physical and chemical stimulation and stress, etc. will promote the reduction of the normal function of the skin, due ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/68A61K8/60A61Q19/00A61P17/04
CPCA61K8/9794A61K8/68A61K8/602A61Q19/00A61Q19/005A61P17/04A61K2800/592A61Q19/007A61P17/16
Inventor 李坰录金京珉金秀颖姜芝美申素荣朴志勳朴尽五李知愿李慧子金地慧金昈永
Owner AMI COSMETIC CO LTD
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