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Essence lotion composition containing lipidosome with pore shrinking effect and preparation method of essence lotion composition

A liposome and composition technology, which is applied in the field of daily chemicals, can solve the problems of affecting the stability of active substances, poor transdermal efficiency of active substances, and inconspicuous effects, and achieve effective transdermal delivery, shrink pores, and synergistic Improves the effect of pores

Active Publication Date: 2022-01-04
湖北省麦诗特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the simple superposition of ingredients that have the effect of shrinking pores is difficult to achieve the purpose of shrinking pores in an all-round way.
Moreover, simply adding various components into skin care products will result in poor transdermal efficiency of active substances, insignificant effect, and will also affect the stability of active substances.

Method used

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  • Essence lotion composition containing lipidosome with pore shrinking effect and preparation method of essence lotion composition
  • Essence lotion composition containing lipidosome with pore shrinking effect and preparation method of essence lotion composition
  • Essence lotion composition containing lipidosome with pore shrinking effect and preparation method of essence lotion composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0078] An essence milk composition containing pore-shrinking effect liposomes, the ratio of raw material components is shown in Table 1 below.

[0079] The raw material component distribution ratio (unit: mass %) of table 1 embodiment 1-3

[0080]

[0081]

Embodiment 1

[0082] The preparation method of the essence milk composition containing the pore-shrinking effect liposome of embodiment 1 comprises the following process steps:

[0083] 1) Preparation of liposomes: Dissolve 1000mg soybean lecithin and 200mg cholesterol in 30mL ether and stir to dissolve for half an hour to fully dissolve to obtain an oil phase; 66mg Ossia solstice extract, 44mg Lentil seed extract, 22mg Pine thorn The algae extract was dissolved in 10 mL of deionized water to obtain the water phase, and the water phase was slowly added to the oil phase; under ice bath conditions, the mixed solution was ultrasonicated for 10 minutes using a cell ultrasonic pulverizer to emulsify it to form a W / O emulsion; The emulsion was transferred to a rotary evaporator, and evaporated under reduced pressure for 60 minutes to remove ether, so that the emulsion gradually formed a gel; after continuing to add an appropriate amount of phosphate buffer solution of pH=7.4 to the gel, continue t...

Embodiment 2

[0087] The preparation method of the essence milk composition containing the pore-shrinking effect liposome of embodiment 2 comprises the following processing steps:

[0088] 1) Preparation of liposomes: Dissolve 500mg of soybean lecithin and 250mg of cholesterol in 20mL of ether and stir to dissolve for half an hour to fully dissolve to obtain an oil phase; 51mg of Ossia solstice extract, 34mg of lentil seed extract, 17mg of pine thorn The algae extract was dissolved in 15 mL of deionized water to obtain the water phase, and the water phase was slowly added to the oil phase; under ice bath conditions, the mixed solution was ultrasonicated for 8 minutes using a cell ultrasonic pulverizer to emulsify it to form a W / O emulsion; The emulsion was transferred to a rotary evaporator, and the ether was evaporated under reduced pressure for 30 minutes to remove the ether, so that the emulsion gradually formed a gel; after continuing to add an appropriate amount of phosphate buffer solu...

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Abstract

The invention discloses an essence lotion composition containing pore-shrinking lipidosome and a preparation method of the essence lotion composition. The essence lotion composition contains: 1.0-25.0 percent of pore-shrinking lipidosome, 5.0 to 35.0 percent of emollient, 0.5 to 20.0 percent of emulsifier, 0.1 to 15.0 percent of filler, 0.2 to 8.0 percent of thickener, 0.5 to 2.0 percent of preservative, 0.2 to 1 percent of pH regulator, 0.05 to 0.8 percent of daily essence and the balance deionized water. The pore-shrinking lipidosome contains the following main functional components: a marrubium vulgare horehound herb extract, a lens culinaris seed extract and a codium fragile extract. When the three components are wrapped with the liposome by being compounded, the liposome can effectively permeate into the skin to take effect. The essence lotion with the efficacy of shrinking pores of the invention not only can solve the problem of coarse pores caused by a single problem, but also solves the problem of coarse pores caused by multiple factors, has synergistic effects of shrinking skin pores, inhibiting skin grease, accelerating keratinocyte metabolism, strengthening dermal collagen, preventing skin aging and reducing inflammation, and can make the skin become finer and smoother.

Description

technical field [0001] The invention relates to a skin care product and its preparation method and application, belonging to the technical field of daily chemicals, and more specifically relates to an essence milk composition containing pore-shrinking liposomes and a preparation method thereof. Background technique [0002] In the era of rapid development of skin care products, everyone wants to have delicate and moist skin. However, with the increase of age, the change of personal living habits, the deterioration of the environment, more and more skin problems. Among them, enlarged pores are one of the skin problems that people are more concerned about. [0003] The pores are the openings of the hair follicles, which have many important functions, such as excreting the secretions of the sebaceous glands. Generally speaking, the large pores are mainly caused by skin aging, excessive secretion of oil glands, blockage caused by unclean cleaning, or enlarged pores caused by i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9722A61K8/06A61K8/14A61Q19/00A61Q19/08
CPCA61K8/9789A61K8/9722A61K8/06A61K8/14A61Q19/00A61Q19/08A61Q19/008A61K2800/592A61K2800/5922A61K2800/82Y02A50/30
Inventor 周紫燕杨帆李沫郭苗周正郭阳
Owner 湖北省麦诗特生物科技有限公司
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