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Nano-emulsion with anti-wrinkle effect prepared by D-phase emulsification method and application thereof

A nano-emulsion and emulsification technology, which is applied in the direction of dressing preparations, cosmetic preparations, medical preparations containing active ingredients, etc., can solve the problem of affecting people's visual perception, uneven powder sticking, makeup not sticking, etc. problem, to achieve the effect of reducing small fine lines on the skin, having a good feeling of use, and enhancing skin elasticity

Active Publication Date: 2021-12-03
FOSHAN QIANRU COSMETICS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, many people are very distressed by the wrinkles on their facial skin. On the one hand, the wrinkles on the face will affect people's visual experience as a whole, making them look old and lifeless; on the other hand , it is prone to the phenomenon that the makeup does not stick and the powder is uneven [2]

Method used

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  • Nano-emulsion with anti-wrinkle effect prepared by D-phase emulsification method and application thereof
  • Nano-emulsion with anti-wrinkle effect prepared by D-phase emulsification method and application thereof
  • Nano-emulsion with anti-wrinkle effect prepared by D-phase emulsification method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A nanoemulsion prepared by a D-phase emulsification method, comprising the following components in mass percentage: 0.5% PEG-55 propylene glycol oleate, 1.5% C12-16 alkyl glucoside, 2% star fruit palm kernel oil, new Pentylene glycol dicaprylate / dicaprate 3%, glycerin 5%, butylene glycol 15%, balance water.

[0031] The preparation process of the nanoemulsion prepared by the D-phase emulsification method comprises the following steps: (1) adding PEG-55 propylene glycol oleate, C12-16 alkyl glucoside, star fruit palm kernel oil, neopentyl glycol dioctyl Ester / dicaprate mixed, heated to 80 degrees, dissolved and transparent under stirring, and the oil phase was obtained; (2) The oil phase was added dropwise to the polyol composed of glycerin and butanediol under stirring conditions; (3 ) into water, stir evenly, and then use a 300bar high-pressure homogenizer to process it twice to obtain.

Embodiment 2

[0033] A nanoemulsion prepared by a D-phase emulsification method, comprising the following components in mass percentage: 1.5% PEG-55 propylene glycol oleate, 0.5% C12-16 alkyl glucoside, 5% star palm kernel oil, new Pentylene glycol dicaprylate / dicaprate 10%, glycerin 15%, butylene glycol 15%, balance water.

[0034] The preparation process of the nanoemulsion prepared by the D-phase emulsification method comprises the following steps: (1) adding PEG-55 propylene glycol oleate, C12-16 alkyl glucoside, star fruit palm kernel oil, neopentyl glycol dioctyl Ester / dicaprate mixed, heated to 80 degrees, dissolved and transparent under stirring, and the oil phase was obtained; (2) The oil phase was added dropwise to the polyol composed of glycerin and butanediol under stirring conditions; (3 ) into water, stir evenly, and then use a 300bar high-pressure homogenizer to process it twice to obtain.

Embodiment 3

[0036] A nanoemulsion prepared by a D-phase emulsification method, comprising the following components in mass percentage: 1% PEG-55 propylene glycol oleate, 1% C12-16 alkyl glucoside, 4% star fruit palm kernel oil, new Pentylene Glycol Dicaprylate / Dicaprate 6%, Glycerin 8%, Butylene Glycol 18%, Water balance.

[0037] The preparation process of the nanoemulsion prepared by the D-phase emulsification method comprises the following steps: (1) adding PEG-55 propylene glycol oleate, C12-16 alkyl glucoside, star fruit palm kernel oil, neopentyl glycol dioctyl Ester / dicaprate mixed, heated to 80 degrees, dissolved and transparent under stirring, and the oil phase was obtained; (2) The oil phase was added dropwise to the polyol composed of glycerin and butanediol under stirring conditions; (3 ) into water, stir evenly, and then use a 300bar high-pressure homogenizer to process it twice to obtain.

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Abstract

The invention discloses a nano-emulsion with an anti-wrinkle effect prepared by a D-phase emulsification method and application thereof. The nano-emulsion prepared by adopting the D-phase emulsification method is prepared from the following components in percentage by mass: 0.5-1.5 percent of PEG-55 (Polyethylene Glycol) propylene glycol oleate, 0.5-1.5 percent of C12-16 alkyl glucoside, 5-15 percent of grease, 20-30 percent of polyhydric alcohol and 55-70 percent of water. The invention further provides an anti-aging composition and application thereof, the anti-aging composition is prepared by selecting the pomelo seed extract, the radix ophiopogonis root extract, the silybum marianum fruit extract and the raspberry fruit extract and adopting a modern extraction process, and the anti-aging composition has the effects of inhibiting the activity of matrix metalloproteinase, enhancing skin elasticity and preventing and even reducing small skin wrinkles.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a nanoemulsion with anti-wrinkle effect prepared by a D-phase emulsification method and an application thereof. Background technique [0002] The D-phase emulsification method is a new emulsification method proposed by Sagitani et al. in 1983 based on the PIC emulsification method. In their experiments, fine nanoemulsions were prepared by diluting a surfactant gel (O / D phase) consisting of a surfactant phase (D phase) surrounding oil droplets. It is pointed out in the literature that the formation of O / D gel phase is the key point to prepare nanoemulsions by D phase emulsification method. It is speculated that the O / D phase is related to the special arrangement of surfactants, oils and polyol solutions, and the dynamic movement process of the formulation components during the preparation process determines the formation of nanoemulsions. But in some formula structures, even if the appe...

Claims

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Application Information

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IPC IPC(8): A61K8/06A61K8/86A61K8/60A61K8/92A61K8/37A61K8/34A61K8/9794A61K8/9789A61Q19/08
CPCA61K8/068A61K8/86A61K8/604A61K8/922A61K8/37A61K8/345A61K8/9794A61K8/9789A61Q19/08A61K2800/413A61K2800/805A61K2800/782
Inventor 胡喜芬
Owner FOSHAN QIANRU COSMETICS CO LTD
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