89Zr drug labeling and purifying device and method thereof

Abstract

The invention discloses an 89Zr drug labeling and purifying device. The device comprises a pressure device, a to-be-labeled drug solution raw material bottle, a chelating agent solution raw material bottle, an 89Zr solution raw material bottle, a product bottle, two reaction kettles, two purification columns, two buffer solution raw material bottles, at least five three-way valves and at least two one-way valves. The 89Zr drug labeling and purifying device provided by the invention can be automatically controlled, is simple to operate, is safe and convenient, and can effectively reduce the ionizing radiation exposure of operators; the labeling process and the purification process can be carried out in the device, isotope pollution is not prone to occurring, and 89Zr medicine labeling and purification can be efficiently, rapidly and accurately completed; the device provided by the invention is used for labeling and purifying the 89Zr medicine, the operation is easy, the marking can be efficiently and quickly completed, and the radiochemical purity of the marked medicine can reach 95% or above.

Description

technical field [0001] The present invention relates to a 89 Zr drug labeling and purification device and method thereof. Background technique [0002] Currently, in the synthesis of radiopharmaceuticals, manual methods are mainly used. In the actual operation process, it will bring greater risks to the staff and is prone to isotope contamination. Therefore, urgently need to provide a kind of marking personnel and 89 Zr source contact time is short, avoid ionizing radiation due to long-term contact, high safety factor 89 Zr drug labeling and purification device. Contents of the invention [0003] The technical problem to be solved in the present invention is in order to overcome in prior art 89 When labeling and purifying Zr drugs, the manual method will bring greater risks to the staff, the safety factor is low, and it is prone to defects of isotope contamination, which provides a 89 The Zr drug labeling and purification device and method thereof effectively reduce ...

AI Technical Summary

Problems solved by technology

[0003] The technical problem to be solved in the present invention is in order to overcome in prior art 89 When labeling and purifying Zr drugs, the manual method will bring greater risks to the staff, the safety factor is low, and it is prone to defects of isotope contamination, which provides a 89 The Zr drug labeling and purification device and method thereof effectively reduce the ionizing radiation exposure of operators, and can efficiently, quickly and accurately complete the 89 Zr drug labeling and purification, and the operation is simple, safe and convenient

Images