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Pharmaceutical composition, pharmaceutical preparation and method for preventing and controlling phyllotreta striolata

A technology for flea beetles and medicinal preparations, applied in the fields of botanical equipment and methods, animal repellents, plant growth regulators, etc. Reduced risk of spreading pathogenic bacteria, improved control effect, reduced root wound effect

Active Publication Date: 2021-10-01
CAC NANTONG CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the occurrence of flea beetle harm is large, it is difficult to control its harm only by agricultural control and physical control, and chemical control must be used. Carry out the toxicity test to determine the preferred formula, determine the best formula is when the ratio of thiatan and phoxim is 15:14, the co-toxicity coefficient reaches the best, and the application of this control agent can effectively prevent and control the flea beetle adults and larvae. growth; however, the organophosphorus component phoxim in this formula has toxicity and residual problems, which limit the application of the agent
CN105009886A discloses a method for preventing and controlling the flea beetle of tomato, which combines ecological management, agricultural control, biological control, biological control, physical control and chemical control; wherein, the plant extract used in biological control Including matrine or quercetin, the method of chemical control is to spray 25g / L deltamethrin EC 2000-2500 times; however, with the widespread use of pyrethroid insecticides, flea beetle Resistance to it has developed, and the insecticidal efficiency has been greatly reduced
CN1918995A discloses a pesticide composition of rotenone and cyfluthrin and its application as an insecticide. The pesticide composition is composed of the following components and percentages by weight: 0.1-10.0% of rotenone, 4.0-30.0% of cyfluthrin, and dosage assistant; the pesticide composition can be prepared into formulations such as emulsifiable concentrate, microemulsion, water emulsion or wettable powder, which can effectively prevent and control various agricultural pests, especially vegetable pests such as flea flea beetle; however, cyfluthrin Also facing the problem of drug resistance
[0005]Comprehensive production of pesticide control, organophosphorus pesticides such as chlorpyrifos, phoxim and profenofos have been used to control flea beetle, due to toxicity and residues, etc., will be withdrawn from the market; pyrethroid insecticides such as cypermethrin, bifenthrin and lambda-cyhalothrin have produced significant drug resistance due to long-term use; neonicotinoid insecticides and new heterocyclic Pesticides are currently mainstream products, but due to frequent use or irrational use, resistance has developed in some areas, and rational rotation or slow use is required

Method used

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  • Pharmaceutical composition, pharmaceutical preparation and method for preventing and controlling phyllotreta striolata
  • Pharmaceutical composition, pharmaceutical preparation and method for preventing and controlling phyllotreta striolata
  • Pharmaceutical composition, pharmaceutical preparation and method for preventing and controlling phyllotreta striolata

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] A pharmaceutical composition for preventing and treating flea beetle, which is composed of active ingredient A and active ingredient B in a mass ratio of 3:7; wherein, the active ingredient A is compound 4, and the active ingredient B is thiamethoxam.

[0085] The pharmaceutical composition is used to prepare pharmaceutical preparations, the dosage form is seed treatment dispersible granules, and the formula is as follows:

[0086] 15 parts of compound 4, 35 parts of thiamethoxam, 2 parts of sodium lauryl sulfate, 3 parts of phenol sulfonate, 3 parts of starch, 4 parts of desmectite, 2 parts of polyethylene glycol, 2 parts of permanent Red and white carbon black are supplemented to 100 parts; the above components are mixed uniformly to prepare seed treatment dispersible granules with a mass percentage of the pharmaceutical composition of 50%.

Embodiment 2

[0088] A pharmaceutical composition for preventing and treating flea beetle, which is composed of active ingredient A and active ingredient B in a mass ratio of 1:1; wherein, the active ingredient A is compound 8, and the active ingredient B is clothianidin.

[0089] The pharmaceutical composition is used to prepare pharmaceutical preparations, the dosage form is a seed treatment suspension, and the formula is as follows:

[0090] 10 parts of compound 8, 10 parts of clothianidin, 3 parts of polycarboxylate, 2 parts of polyoxyethylene polyoxypropylene block copolymer, 3 parts of cellulose derivatives, 0.28 parts of xanthan gum, 2 parts of white carbon black, 0.2 parts of Cathone, 5 parts of ethylene glycol, 2 parts of permanent red, and water make up to 100 parts; the above-mentioned components are mixed uniformly, and the seed treatment suspension concentrate with a mass percentage of 20% of the pharmaceutical composition is prepared .

Embodiment 3

[0092] A pharmaceutical composition for preventing and treating flea beetle, which is composed of active ingredient A and active ingredient B at a mass ratio of 1:3; wherein, the active ingredient A is compound 1, and the active ingredient B is dinotefuran.

[0093] The pharmaceutical composition is used to prepare pharmaceutical preparations, and the dosage form is a soluble agent, and the formula is as follows:

[0094] 3 parts of compound 1, 9 parts of dinotefuran, 5 parts of fatty alcohol polyoxyethylene ether, 5 parts of polyaryl phenyl polyoxyethylene ether, 5 parts of castor oil polyoxyethylene ether, 8 parts of N,N-dimethyl ethyl ether Amidoamine, 15 parts of n-butanol, 5 parts of methanol, and water make up to 100 parts; the above components are mixed uniformly to prepare a soluble agent with a mass percentage of the pharmaceutical composition of 12%.

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PUM

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Abstract

The invention provides a pharmaceutical composition, a pharmaceutical preparation and a method for preventing and controlling phyllotreta striolata. The pharmaceutical composition comprises an effective component A and an effective component B; the effective component A comprises an m-diamide compound with a structure as shown in a formula I; and the effective component B comprises any one or a combination of at least two of rotenone, sophocarpidine, azadirachtin, metarhizium anisopliae, beauveria bassiana, bacillus thuringiensis, dinotefuran, acetamiprid, thiamethoxam, clothianidin, spinetoram, chlorfenapyr, pyridaben, thiocyclam and diafenthiuron. The effective component A and the effective component B are compounded and have complementary action modes and synergistic interaction, the prevention and control effect is remarkably improved, and the composition has the characteristics of low dosage, high efficiency and environmental protection. According to the method for preventing and controlling phyllotreta striolata, the pharmaceutical composition is combined with multiple application modes, and especially through application of seed treatment, root irrigation treatment or broadcast application treatment, the method has the advantages of early prevention and long lasting effect.

Description

technical field [0001] The invention belongs to the technical field of insecticides, and in particular relates to a pharmaceutical composition, pharmaceutical preparation and method for preventing and treating flea beetle. Background technique [0002] Phyllotreta striolata belongs to the family Coleoptera Chrysanthemum and is a worldwide pest that seriously harms vegetables, mainly harming cruciferous vegetables, such as Chinese cabbage, mustard greens, radishes, cabbage, rapeseed and cabbage. The flea beetle is widely distributed in many countries and regions such as Asia, Europe, and North America. It is distributed all over China, from Heilongjiang and Inner Mongolia in the north to Guangdong and Fujian in the south, Gansu in the west, and Shanghai and Jiangsu in the east. area. In recent years, with the adjustment of the agricultural industry structure, the planting area of ​​cruciferous vegetables has continued to expand, and there is no fallow period in most areas, c...

Claims

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Application Information

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IPC IPC(8): A01N37/46A01N41/10A01N51/00A01N47/40A01N43/22A01N43/36A01N43/58A01N43/32A01N47/30A01P7/04
CPCA01N37/46A01N41/10A01N2300/00A01N51/00A01N47/40A01N43/22A01N43/36A01N43/58A01N43/32A01N47/30Y02A50/30
Inventor 倪珏萍相君成吕亮洪湖
Owner CAC NANTONG CHEM
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