Compound lidocaine gel patch

Abstract

The invention relates to a compound lidocaine / prilocaine gel patch. The gel patch is prepared from following components in percentage by weight: 4%-8% of lidocaine hydrochloride, 4%-8% of prilocaine hydrochloride, 2%-5% of a framework material, 5%-10% of a filler, 20%-30% of an adhesive, 3%-9% of a tackifier, 1%-5% of a cross-linking agent, 2%-4% of a transdermal absorption enhancer, 30%-50% of a humectant, 0.005%-0.02% of a preservative, 0.005%-0.02% of a complexing agent and 0.5%-2% of a stabilizer. The compound lidocaine / prilocaine gel patch is stable in quality, good in treatment effect, simple in preparation process and capable of realizing industrial production.

Description

technical field [0001] The invention relates to the field of medicines, in particular to an analgesic gel patch. Background technique [0002] Pain is listed as the "fifth vital sign" of the human body and is a common adverse human experience. Epidemiological surveys show that the incidence of chronic pain in adults is 20%-60%, and the incidence of pain with neuropathic features is 6.9%-10% in the population, of which local neuropathic pain accounts for 60%. Chronic pain can lead to reduced ability to work, and its accompanying emotional and sleep disturbances have a serious impact on quality of life. However, pain management is complex and often requires a combination of multiple treatments, and many patients are not satisfied with pain treatment outcomes. Treatment of neuropathic pain is particularly suboptimal, with patients often relapsing and half suffering from inadequate pain relief. [0003] Herpes zoster is an acute central nervous system infection that primarily...

AI Technical Summary

Problems solved by technology

[0009] At present, the compound lidocaine / prilocaine gel patch with stable and controllable quality and good analgesic effect has not been reported yet.

Images