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Multilayer medium photoacoustic tomography method

A multi-layer media, photoacoustic tomography technology, applied in medical imaging, tomography for diagnosis, applications, etc., can solve the problems of low modeling accuracy, complex algorithm calculation, etc., achieve high modeling accuracy, solve algorithm Simple, high-contrast effects

Active Publication Date: 2021-09-17
SOUTHEAST UNIV
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Problems solved by technology

[0004] Aiming at the defects of the prior art, the present invention provides a multi-layer medium photoacoustic tomography method, which solves the current technical problems of low modeling accuracy and complex algorithm calculations for the photoacoustic imaging method

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Embodiment Construction

[0037] The specific embodiments of the present invention will be described below in conjunction with the accompanying drawings.

[0038] A multi-layer medium photoacoustic tomography method of the present application, comprising the following steps:

[0039] Step 1, using pulsed light to illuminate the multi-layer medium to be imaged, using multiple transducers set in the outer medium to receive the acoustic signals generated by the multi-layer medium from multiple angles and different positions, and each Perform Fourier transform on the signal received by the transducer to form a sound pressure spectrum;

[0040] Step 2, performing discretized grid division on the multi-layer medium based on the geometric parameters of the multi-layer medium according to the required imaging resolution requirements;

[0041] Step 3, based on the result of discretized grid division in step 2, according to the frequency-domain sound propagation equation, select a certain number of discrete fre...

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Abstract

The invention relates to a multilayer medium photoacoustic tomography method. The multilayer medium photoacoustic tomography method comprises the following steps of: illuminating a multilayer medium to be imaged by using pulsed light, receiving acoustic signals generated by the multilayer medium from different positions at multiple angles by using a plurality of transducers arranged in an outer layer medium, and performing Fourier transform on the signals received by each transducer, forming a sound pressure spectrum; according to a resolution requirement of required imaging, carrying out discretization grid division on the multilayer medium based on geometric parameters of the multilayer medium; according to a frequency domain sound propagation equation, selecting a certain number of discrete frequency points, and constructing a model matrix; combining the model matrix with the sound pressure spectrums corresponding to a certain number of discrete frequency points, and constructing a linear equation set; and solving and optimizing the linear equation set. According to the photoacoustic tomography method, the quality of the photoacoustic tomography image in the multilayer heterogeneous medium can be remarkably improved, accurate initial sound pressure distribution is obtained, and high-resolution and high-precision imaging can be completed by automatically setting image resolution according to actual needs.

Description

technical field [0001] The invention relates to the technical field of photoacoustic imaging, in particular to a multilayer medium photoacoustic tomography method. Background technique [0002] As a new non-ionizing imaging method, photoacoustic imaging has the characteristics of optical imaging contrast and acoustic imaging resolution, and is being widely used in biomedicine, clinical treatment and other medical fields. In recent years, photoacoustic imaging of multilayer media has aroused the research interest of many experts and scholars, because the inconsistency of acoustic parameters will have a huge impact on imaging, for example, in photoacoustic transcranial imaging, the gap between the skull and brain tissue The serious acoustic impedance mismatch between them leads to the amplitude attenuation and phase change of the photoacoustic signal, and these changes will cause serious errors in the reconstructed image using the traditional photoacoustic imaging algorithm. ...

Claims

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Application Information

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IPC IPC(8): A61B5/00G06F30/23G06F17/12G06F17/16G06F111/04
CPCA61B5/0042A61B5/0066A61B5/0073G06F30/23G06F17/12G06F17/16A61B2576/026G06F2111/04
Inventor 张辉吴欣恺沈鹏倪中华殷国栋
Owner SOUTHEAST UNIV
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