Novel hymexazol oxyglycoside conjugate as well as preparation and application thereof

A technology for oxamethoxine and its conjugate, which is applied to a new type of oxamethoxine conjugate and its preparation and application fields, can solve the problems of reduced soil fertilizer efficiency, poisonous beneficial organisms, restricted crop growth, and the like, To achieve the effect of promoting plant growth activity, good antifungal and high selectivity

Active Publication Date: 2021-08-17
INST OF OCEANOLOGY - CHINESE ACAD OF SCI
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the widespread use of hymexazol, some of its shortcomings have been exposed
Bear the brunt, it has been found that some fungi have developed resistance to hymexazol, and secondly, hymexazol has a toxic effect on beneficial organisms in the soil, such as earthworms, beneficial fungi, etc.
In addition, hymexazol can bind metal ions such as iron and aluminum in the soil, resulting in a decrease in soil fertilizer efficiency, resulting in limited crop growth. Therefore, it is imminent to modify the structure of hymexazol

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Novel hymexazol oxyglycoside conjugate as well as preparation and application thereof
  • Novel hymexazol oxyglycoside conjugate as well as preparation and application thereof
  • Novel hymexazol oxyglycoside conjugate as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1: 3- (β-D-gylancose) -5-methylisodazole synthesis See figure 1 :

[0039] The mixed solution of 75 ml of pyridine and 50 ml of acetic anhydride was placed on ice. After the cooling was complete, 10 g of glucose was added therein, and after complete dissolution. The temperature of the reaction system is slowly warmed to room temperature, the entire reaction in N 2 The reaction solution was poured into ice water after 15 h, then filtered, dried to give a 15.1 g of a white solid product full acetylated glucose.

[0040] The 33% bromide liquid containing ice acetic acid was pre-cooled at 0 ° C, and then 10 g of a polyacetylated glucose was added (1 g of 1 g, after 5 minutes, completed) to the reaction liquid, and all raw materials were added After the slow temperature increases to room temperature, it continued to react 1H, TLC monitoring the feedstock was exhausted, 40 ml of ice water was added to the reaction mixture, stirred for 30 min, extracted three times with 80...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method and application of a novel hymexazol oxyglycoside conjugate bactericide. Galactose, mannose, glucose, mannosamine, galactosamine, glucosamine, N-acetyl-galactosamine, N-acetyl-mannosamine and acetylglucosamine are respectively conjugated with hymexazol to obtain a series of hymexazol oxyglycoside conjugates. The structural general formula of the compound is shown as I, R is hydroxyl, oxyacetyl, amino and acetamido, and R1 is hydrogen and acetyl. The conjugate disclosed by the invention is novel in structure, has good solubility and antifungal activity, and has the potential of becoming a novel green bactericide.

Description

Technical field [0001] The present invention is belonging to a bactericide, and more particularly to a novel variconcoside conjugate and its preparation and application thereof. Background technique [0002] Since the Second World War, traditional agriculture has undergone earth-shaking changes, and single-made cultivation has replaced round, a large number of chemical synthetic pesticides and fertilizers have replaced animal fertilizers. At the same time, the production of soil fertility is also increased, and the soil micro-ecosystem is changed. This change is the most direct harm to soil propagation disease presentation exponential growth. Soil fungal disease is a major murder disease, and its pathogens mainly include chain cyclosporospore, pepperpatochemile, spyfacial fusse, and ribbutter. The complexity of the soil environment and certain fungi unique existence is the maximum resistance of soil propagation disease. Traditional treatment is to eradicate pathogens in soil, suc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07H17/00C07H1/00C07H1/06A01N43/80A01P3/00A01P21/00
CPCC07H17/00C07H1/00C07H1/06A01N43/80
Inventor 秦玉坤高堃李鹏程邢荣娥刘松于华华陈晓琳耿昊
Owner INST OF OCEANOLOGY - CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap