Abamectin micro-droplet preparation device and method based on flow focusing technology

Abstract

The invention discloses an abamectin micro-droplet preparation device and method based on a flow focusing technology, the abamectin micro-droplet preparation device comprises a heat preservation box, a feeding tank, an outer needle head, an inner needle head, a cavity chamber, an injection pump and a condensation pipe, the feeding tank is arranged in the heat preservation box, the inner needle head is embedded in the outer needle head, the cavity chamber is filled with driving liquid, a driving phase inlet is formed in the side face of the cavity chamber, a driving phase outlet is formed in the center of the bottom of the cavity chamber, the feeding tank is connected with the outer needle head through a pipeline, and the liquid outlet end of the injection pump is communicated and connected with the upper end of the inner needle head through a pipeline. A flow focusing technology is applied to preparation of a abamectin microcapsule, the problems that the pesticide effect is reduced and the stability is poor due to the fact that the abamectin is rapidly passivated when encountering soil are solved, the prepared abamectin microcapsule has a good slow-release effect and a high embedding rate, and the utilization rate of the abamectin is increased; the structure is simple, the operation is convenient, the preparation cost of the microcapsule is obviously reduced, and the device and the method are suitable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of preparation of pesticide microcapsules, in particular, the invention relates to a device and method for preparing abamectin microdroplets based on flow focusing technology. Background technique [0002] Abamectin is a sixteen-membered cyclic lactone biopharmaceutical extracted from the metabolites fermented by Streptomyces avermanii. Although abamectin has a direct contact effect on predatory insects and parasitic natural enemies, it has little damage to beneficial insects because of the small residue on the plant surface; There is no cumulative effect; it is widely used in the control of parasites and about 80 kinds of crop pests. It is an excellent broad-spectrum insecticide and acaricide and one of the most promising biopesticides at present, but Abamectin is unstable in water , see ultraviolet light easy to decompose. [0003] Today, abamectin has appeared in dosage forms such as suspension concentr...

AI Technical Summary

Problems solved by technology

It has the advantage of commercial production without considering material adaptability and refined production, but this method is not suitable for the preparation of pesticides containing amine groups, hydroxyl groups, and acid-sensitive pesticides. There are many such pesticides, such as: Abamectin contains primary and secondary hydroxyls and belongs to this category

If the interfacial polymerization method is still used, other reactive monomers need to be added, the control variable factors increase, and the preparation cost increases

[0006] For the preparation of pesticides containing amine groups, hydroxyl groups, and acid-sensitive compounds, the complex coacervation method has high production costs and low encapsulation efficiency, and is not suitable for commercial production.

[0007] Emulsification-solvent evaporation method, this method needs to consume a large amount of organic solvents, which has adverse effects on the environment and the human body, this method needs to use stirring or ultrasonic methods to reduce the particle size, and the particle size cannot be precisely controlled

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