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Machine learning diabetes onset risk prediction method and application

A technology of machine learning and risk prediction, applied in the fields of instrumentation, informatics, medical informatics, etc., can solve problems such as inconsistent standards, poor individual pertinence of model building, low efficiency of risk prediction, etc., and achieve high predictive ability and good stability Effect

Inactive Publication Date: 2021-05-11
TIANJIN MEDICAL UNIV
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention overcomes the problems of low efficiency of risk prediction for medical personnel, non-uniform standards, subjective differences, low predictive ability of simple prediction models, and poor individual pertinence of traditional predictive factor construction models

Method used

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  • Machine learning diabetes onset risk prediction method and application

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Embodiment 1

[0034] Such as figure 1 As shown, the present invention provides a diabetes risk prediction model based on machine learning and metabolic features. The method includes: performing metabolomics detection on the blood samples of the population to be predicted, and obtaining metabolomics characteristic data; preprocessing the collected raw data, using a random forest model to fill in missing values, and performing normalization and discretization on the data Processing; use the preprocessed data to predict using a model based on random forest and support vector machine, and output the prediction result. If the output result is 1, there is a risk of diabetes, and if the output result is 0, there is no diabetes. disease risk.

[0035] As mentioned above, the embodiments of the present invention provide a diabetes risk prediction method based on machine learning algorithms and metabolic characteristics, using random forest and support vector machine algorithm-based technologies, co...

Embodiment 2

[0037] See figure 1 : After a patient draws blood in the hospital, the staff analyzes the blood sample through a high-throughput analysis instrument to obtain amino acid and carnitine data; fills the amino acid carnitine data into the preprocessing module and runs the preprocessing program; The data is put into the model, and the prediction program is run; the prediction result is output, and the prediction result of a patient's metabolic data using the model is 1, indicating that he has a risk of diabetes.

Embodiment 3

[0039] After a subject obtains a metabolic analysis report from a company, he submits the report to the staff, and the staff uses the preprocessing module to preprocess and analyze the data based on the test results. The preprocessed data is used to make predictions using the model. If the result of the prediction output is 0, the subject has no risk of diabetes.

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Abstract

The invention provides a machine learning diabetes onset risk prediction method. The method comprises the following steps: a data acquisition module for acquiring metabonomics data; a data preprocessing module for preprocessing the acquired data; a machine learning module for constructing a prediction model based on a machine learning algorithm and metabonomics data for the purpose of diabetes risk prediction; and a display output module for testing the obtained to-be-predicted sample and outputting a prediction result. If the prediction result is 1, the diabetes risk exists, and if the prediction result is 0, the diabetes risk does not exist. According to the embodiment of the invention, the diabetes risk prediction model is constructed by combining metabonomics characteristics based on technologies mainly based on the random forest and the support vector machine algorithm. The method can be used for improving decision-making efficiency, guiding non-medical personnel to carry out disease risk detection or assisting clinical decision-making, and achieving the purposes of three-level prevention of diseases and promotion and development of health of the whole people.

Description

technical field [0001] The invention belongs to a method for constructing a model by using a machine learning algorithm and adopting a novel predictor to predict the risk of diabetes onset. Background technique [0002] Disease risk prediction is mainly used to assist clinical decision-making, to assist the health detection of sensitive groups, and to detect disease risk for non-medical personnel. [0003] Type Ⅱ diabetes is a common metabolic disease in the department of endocrinology, accounting for more than 90% of diabetic patients. At present, the prediction of diabetes risk mainly includes two prediction methods based on the judgment of medical staff based on professional knowledge and the simple prediction model constructed by using traditional risk factors. Judging diseases through medical staff's experience and self-learning is the main clinical method at present. However, there are problems such as large subjective differences and low efficiency in medical staff's...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H50/70G16H15/00G06K9/62
CPCG16H50/30G16H50/70G16H15/00G06F18/2411G06F18/24323
Inventor 房中则刘永哲高小茜王婉莹李欣
Owner TIANJIN MEDICAL UNIV
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