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Implantable extensible multi-mode recording and photostimulation brain-computer interface device

A brain-computer interface, multi-modal technology, applied in the field of biomedical electronics, to achieve the effect of reducing implantation immune rejection, solving poor mechanical hardness matching, and reducing potential damage

Pending Publication Date: 2021-03-09
NORTHWESTERN POLYTECHNICAL UNIV
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Problems solved by technology

However, there is no implantable and extensible brain-computer interface device with synchronous multi-modal recording and deep brain light stimulation function integration, and good mechanical matching with brain soft tissue, and this device has important use value for neuroscience research

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  • Implantable extensible multi-mode recording and photostimulation brain-computer interface device
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  • Implantable extensible multi-mode recording and photostimulation brain-computer interface device

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specific Embodiment

[0044] refer to figure 1 As shown, an implantable extensible multi-mode recording and optical stimulation brain-computer interface device of the present invention includes a deep penetration electrode part 1 and a surface plane electrode part 2 . Among them, the surface plane electrode part 2 mainly includes an array of cortical recording electrode points 3, and the attachment position is the cerebral cortex area 6; the deep layer penetrating electrode part 1 mainly includes an array of deep layer recording electrode points 4 and micro LED chips 5. The implanted location is the deep brain region7. In the deep penetrating electrode part 1 and the surface plane electrode part 2, the number and size of all recording electrode points and micro-LED chips 5 can be designed according to actual needs. This embodiment is mainly for rodent mice.

[0045] refer to figure 2 As shown, the deep recording electrode point 1 is connected to the interface terminal through the recording serpe...

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Abstract

The invention discloses an implantable extensible multi-mode recording and photostimulation brain-computer interface device. The device comprises a deep penetration electrode part and a surface planeelectrode part. The deep penetration electrode part comprises a deep recording electrode point and a micro LED chip packaged in elastic transparent silica gel, wherein the surface plane electrode partcomprises a cortex recording electrode point. The micro LED chip emits light to work, neurons are activated to perform potential release, a cerebral cortex electric signal is collected through the cortex recording electrode point, and meanwhile the deep recording electrode point collects a single neuron pulse signal; and the cerebral cortex electric signal and the single neuron pulse signal are transmitted to an interface end at the same time. The device has deep brain photostimulation and synchronous multi-spatial-scale neural signal monitoring capacity and has multi-spatial-scale neural signal monitoring capacity, meanwhile, the unified interface end is used, and the system integration level and long-term implantation reliability are effectively improved.

Description

technical field [0001] The invention belongs to the technical field of biomedical electronics, and in particular relates to a brain-computer interface device. Background technique [0002] In recent years, optogenetics has brought a revolutionary impact on neural circuit research. Compared with neural regulation methods such as electrical stimulation and drug stimulation, optical stimulation has millisecond-level time response accuracy and can selectively regulate specific types of neurons. Combined with electrophysiological recordings to form a closed-loop system, it is possible to precisely probe the causal relationship between specific neural circuits and brain function. Compared with optical transmission forms such as optical fibers and optical waveguides, micro-LED chips are small in size and low in power consumption, and are suitable for in-situ integration to provide high-resolution light stimulation. In view of the extremely soft characteristics of brain tissue, it ...

Claims

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Application Information

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IPC IPC(8): A61B5/268A61B5/273A61B5/293A61B5/294A61B5/377A61B5/386A61B5/388G06F3/01
CPCG06F3/015A61B2562/0209A61B2562/164A61B2503/40A61B2503/42A61B2562/125
Inventor 吉博文皇甫帅祺常洪龙冯慧成周宇昊张凯
Owner NORTHWESTERN POLYTECHNICAL UNIV
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