Preparation method of cellulose antibacterial material modified based on natural active component chlorogenic acid

Abstract

The invention discloses a preparation method of a cellulose antibacterial material modified based on a natural active component chlorogenic acid, which comprises the steps of dissolving cellulose in amixed aqueous solution of sodium hydroxide and urea to prepare a cellulose solution; adding anhydrous sodium sulfate into the obtained cellulose solution, stirring, and freezing until the cellulose solution is solidified; soaking the solidified mixture in water until the material floats on the water surface to obtain a cellulose material; mixing the cellulose material with a sodium hydroxide aqueous solution and epoxy chloropropane, and then cleaning the cellulose material with deionized water until the sodium hydroxide aqueous solution and the epoxy chloropropane have no residue; and takingout the cellulose material, a sodium carbonate solution and a chlorogenic acid ethanol solution, and washing the cellulose material with water until the cellulose material is not decolorized to obtainthe chlorogenic acid modified cellulose antibacterial material. The chlorogenic acid and the cellulose are covalently connected by adopting the epoxy chloropropane, so that the antibacterial agent can be more stably grafted on the surface of the cellulose, the antibacterial agent is prevented from falling off, and a good antibacterial effect is kept for a long time.

Description

technical field [0001] The invention relates to a preparation method of an antibacterial material, in particular to a preparation method of a cellulose antibacterial material modified based on natural active ingredient chlorogenic acid. Background technique [0002] In recent years, chlorogenic acid, as a natural plant active ingredient, has attracted widespread attention for its antibacterial activity. Chlorogenic acid is an esterification product of caffeic acid and quinic acid produced through the phenylpropionic acid synthesis pathway in the plant's own growth and metabolism. It is commonly found in honeysuckle, Eucommia ulmoides, coffee beans and mulberry leaves. Chlorogenic acid has the functions of regulating blood sugar, lipid metabolism, anti-cancer and lowering blood pressure, so it is often used as a health care product. In addition, chlorogenic acid has good antibacterial effect on bacteria (such as Escherichia coli and Staphylococcus aureus, etc.) and fungi (Ca...

AI Technical Summary

Problems solved by technology

This kind of method requires multi-process processing, and it takes a lot of energy and cost to make antibacterial agents. During the process, it may cause pollution, and even contact with toxic or irritating drugs, which is very dangerous

[0007] All in all, the use of non-covalent linkage to load antibacterial agents can easily lead to the loss of antibacterial agents, weaken the antibacterial effect, and reduce the service life, while the commonly used antibacterial agents made of precious metals such as silver and titanium are expensive to prepare, and the process is complicated and easy to cause pollution.

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