Oral care composition

A technique for oral care and composition, which is applied in the field of oral care composition and its preparation, can solve the problems of expensive medicines and side effects, increase saliva secretion, thick gargle, etc., achieve excellent biocompatibility, simple production process, Reduce the effect of evaporation

Pending Publication Date: 2021-01-15
SHAANXI BIO REGENERATIVE MEDICINE CO LTD
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The application of some drugs only has a certain effect on stimulating saliva secretion and improving oral symptoms; and the current drugs are limited to stimulating muscarinic choline receptors, such as pilocarpine, etc.
In addition, thiopenthione (also known as bilivitamin) can increase saliva secretion for patients with mild salivary secretion dysfunction. It is impossible to take medicines for a long time
Although there are a variety of saliva substitutes on the market to relieve oral symptoms, such as artificial saliva and mouth moisteners, these only have a moisturizing function and have no other medical effects, and their ingredients mostly contain plant extracts
[0006] Patent CN108175736A discloses a gargle and its preparation method. The gargle is prepared by mixing the following raw materials in parts by weight: 0.008-0.03 parts of Melaleuca alternifolia essential oil, 1-2 parts of green tea water extract, honeysuckle water extract 0.008-0.02 parts of liquid, 0.8-1.2 parts of citric acid, 1.2-1.8 parts of natural honey, 1.4-1.8 parts of xylitol, 0.008-0.02 parts of menthol, 1 part of 1,3-butanediol and 92.13-94.576 parts of purified water part; the gargle formula of the invention is safe and can effectively inhibit hemolytic streptococcus in the oral cavity; but the gargle contains plant extracts, the gargle is thick, not refreshing enough and has a strong foreign body sensation after use

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Oral care composition
  • Oral care composition
  • Oral care composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] The invention provides an oral care composition, which comprises:

[0085] 2 parts polysorbate-80, 10 parts glycerin, 0.3 parts sodium chloride, 0.1 parts sodium edetate, 0.1 parts citric acid, 0.1 parts sodium citrate, 0.02 parts sodium methylparaben, 0.02 parts paraben sodium ester, 0.2 parts of potassium sorbate and appropriate amount of water.

[0086] The preparation method of present embodiment oral care composition is as follows:

[0087] S1. Heat an appropriate amount of water and 10 parts of glycerin to 70°C, stir at 250r / min for 10min, and cool to 30°C;

[0088] S2. Add 5.2 parts of polysorbate-80, 0.3 parts of sodium chloride, 0.1 part of sodium edetate, 0.1 part of citric acid, 0.1 part of sodium citrate, and 0.02 parts of methylparaben to the mixed solution obtained in step S1 sodium, 0.02 part of sodium propylparaben and 0.2 part of potassium sorbate, and stirred at 250 r / min for 10 minutes to obtain the oral care composition.

Embodiment 2

[0090] The present invention provides an oral care composition, wherein, according to parts by mass, the composition comprises:

[0091] 8 parts polysorbate-80, 25 parts glycerin, 1 part sodium chloride, 0.8 parts sodium edetate, 0.5 parts citric acid, 0.5 parts sodium citrate, 0.1 part sodium methylparaben, 0.1 part paraben sodium ester, 0.5 part of potassium sorbate and appropriate amount of water.

[0092] The preparation method of present embodiment oral care composition is as follows:

[0093] S1. Heat an appropriate amount of water and 25 parts of glycerin to 80°C, stir at 400r / min for 30min, and cool to 40°C;

[0094] S2. Add 8 parts of polysorbate-80, 1 part of sodium chloride, 0.8 part of sodium edetate, 0.5 part of citric acid, 0.5 part of sodium citrate, and 0.1 part of methylparaben to the mixed solution obtained in step S1 sodium, 0.1 part of sodium propylparaben and 0.5 part of potassium sorbate, and stirred at 400 r / min for 10 minutes to obtain the oral care c...

Embodiment 3

[0096] The invention provides an oral care composition, which comprises:

[0097]5 parts polysorbate-80, 20 parts glycerin, 0.6 parts sodium chloride, 0.3 parts sodium edetate, 0.2 parts citric acid, 0.4 parts sodium citrate, 0.03 parts sodium methylparaben, 0.03 parts paraben sodium ester, 0.25 part of potassium sorbate and appropriate amount of water.

[0098] The preparation method of present embodiment oral care composition is as follows:

[0099] S1. Heat an appropriate amount of water and 20 parts of glycerin to 75°C, stir at 300r / min for 15min, and cool to 35°C;

[0100] S2. Add 5 parts of polysorbate-80, 0.6 part of sodium chloride, 0.3 part of edetate sodium, 0.2 part of citric acid, 0.4 part of sodium citrate, 0.03 part of methylparaben in the mixed solution obtained in step S1 sodium, 0.03 part of sodium propylparaben and 0.25 part of potassium sorbate, and stirred at 300 r / min for 15 minutes to obtain the oral care composition.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides an oral care composition. The composition comprises a solubilizer, a humectant, a stabilizer, a pH regulator, a preservative and water, wherein the solubilizer is selected fromone or more of polysorbate-60, polysorbate-80, polysorbate-85, polyglycerol-3 methyl glucose distearate, polyglycerol-10 stearate, polyglycerol-10 myristate, polyglycerol-10 dioleate, polyglycerol-10laurate, polyglycerol-10 isostearate, polyglycerol-10 oleate, polyglycerol-10 di-isostearate, polyglycerol-6 laurate and polyglycerol-6 myristate. The oral care composition is refreshing in use, freeof foreign matter residues, lasting in moisturizing effect and high in safety.

Description

technical field [0001] The invention relates to the technical field of preparation of daily chemicals, in particular to an oral care composition and a preparation method thereof. Background technique [0002] Xerostomia is the decrease in secretion or increase in consumption of saliva in the oral cavity due to various reasons, and a negative balance of saliva secretion and consumption occurs in the oral cavity, causing dry mouth. With the improvement of people's quality of life and the enhancement of self-care awareness, more and more patients seek medical treatment with oral cavity and throat xerostomia, accounting for about 10% of the population; and among the elderly over 65 years old, more than 30% of patients with xerostomia %. [0003] Xerostomia is the main complaint of dry mouth, a symptom of subjective feeling, and objective dry mouth (negative balance of saliva caused by decreased secretion or increased consumption of saliva in the oral cavity due to various reaso...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/37A61K8/44A61K8/49A61K8/20A61K8/34A61K8/36A61K8/365A61Q11/00
CPCA61K8/4993A61K8/44A61K8/365A61K8/37A61K8/345A61K8/20A61K8/36A61Q11/00
Inventor 周斌
Owner SHAANXI BIO REGENERATIVE MEDICINE CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap