Composite tendon repair material and preparation method thereof

Abstract

The invention relates to a composite tendon repair material. The composite tendon repair material is characterized by comprising a base layer and one or more active units, wherein the base layer and the active units are fixedly arranged with each other; the base layer comprises an extracellular matrix material; each active unit in the active units comprises a first active layer, a second active layer and a covering layer; the first active layer comprises an extracellular matrix material and a first active component; the second active layer comprises an extracellular matrix material and a second active component; and each active unit is prepared by a mechanical compression method. The repair material promotes bone tissue wound surface growth repair and tendon tissue wound surface growth repair at the tendon and bone tearing positions respectively, finally, promotes healing of dead points at the junction of tendons and the bone, and effectively forms a dead-point-like structure from thebone, calcified cartilage and fibrous cartilage to the tendons. By means of the structure, repair of huge rotator cuff tendon tearing can be achieved.

Description

technical field [0001] The invention relates to a medical device for implantation, in particular to a tendon repair material with a composite structure. The material has a growth factor with a gradient change in quantity per unit length, which can effectively realize the establishment of tendon-bone insertion and the effective repair of tendon. The invention further includes a preparation method of the composite tendon repair sheet material. Background technique [0002] The rotator cuff is a cuff-like muscle-like structure formed by the tendons of the supraspinatus, infraspinatus, subscapularis, and teres minor in front, above, and behind the humeral head, and realizes the functions of controlling and turning the arm. When the rotator cuff tendon is subjected to overload stress, it will undergo inflammation and degradation, causing pain, lipidation, and calcification, which will reduce the mechanical properties of the tendon, and eventually partial thickness tear and full-t...

AI Technical Summary

Problems solved by technology

However, pathological studies have shown that the tissue structure of the rotator cuff insertion cannot return to its normal shape after surgical reconstruction, and the main problem is that the fibrocartilage layer in the healed tendon-bone interface cannot be regenerated and is only replaced by scar tissue, resulting in the formation of an indirect insertion. The mechanical properties of the point are far lower than the normal direct stop, and it is easy to re-tear

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