A kind of technology based on medical tablet coating processing

A coating and tablet technology, applied in the direction of making medicines into special physical or taking forms of devices, coatings, etc., can solve the problems of poor moisture-proof and anti-oxidation effects, difficult to achieve moisture-proof and anti-deterioration, and long drying time. , to achieve the effect of easy drying, avoiding stomach discomfort and fast drying

Active Publication Date: 2022-08-09
BEIJING TONGRENTANG XINGAN HEALTH TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the existing coating is usually made of talcum powder, which has poor moisture-proof and anti-oxidation effects, and it is difficult to achieve a good moisture-proof and anti-deterioration effect after the tablet is coated.
Moreover, the existing coating process is usually to dry the tablet after all the coating is complete, which takes a long time and consumes a lot of energy.

Method used

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  • A kind of technology based on medical tablet coating processing
  • A kind of technology based on medical tablet coating processing
  • A kind of technology based on medical tablet coating processing

Examples

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Effect test

Embodiment 1

[0032] A process based on medical tablet coating processing, comprising the following steps: (1) manufacturing coating pulp: mixing talc, hydroxypropyl methylcellulose and nano-silicon dioxide in a mixer to obtain coating pulp , wherein the ratio of parts by weight between the talc, hydroxypropyl methylcellulose, nano-scale silicon dioxide is 2: 1.5: 1.3; be specifically to get 20kg of talc, 15kg of hydroxypropyl methylcellulose , the nanoscale silicon dioxide of 1.3kg is mixed and obtained; (2) preheating tablet: the tablet to be coated is placed in the coating equipment, such as Figure 1-7 As shown, the coating equipment includes an operation room 1, a spray gun 4, a jetting device 2, a feeding device 3 and a recovery device 5; The outer sleeve 21, the air-jet channel provided in the sleeve, the injection member 23 connected with the air-jet channel, and the blower 24, a heating element 25 is arranged between the blower 24 and the sleeve 21, and the heating element 25 passe...

Embodiment 2

[0039] A process based on medical tablet coating processing, comprising the following steps: (1) manufacturing coating pulp: mixing talc, hydroxypropyl methylcellulose and nano-silicon dioxide in a mixer to obtain coating pulp , wherein the ratio of parts by weight between the talc, hydroxypropyl methylcellulose, and nano-scale silicon dioxide is 4:2.5:1.6; specifically, taking 40kg of talc, 25kg of hydroxypropylmethylcellulose , the nanoscale silicon dioxide of 1.6kg is mixed to obtain; (2) preheating tablet: the tablet to be coated is placed in the coating equipment, such as Figure 1-7 As shown, the coating equipment includes an operation room 1, a spray gun 4, a jetting device 2, a feeding device 3 and a recovery device 5; The outer sleeve 21, the air-jet channel provided in the sleeve, the injection member 23 connected with the air-jet channel, and the blower 24, a heating element 25 is arranged between the blower 24 and the sleeve 21, and the heating element 25 passes th...

Embodiment 3

[0042] A process based on medical tablet coating processing, comprising the following steps: (1) manufacturing coating pulp: mixing talc, hydroxypropyl methylcellulose and nano-silicon dioxide in a mixer to obtain coating pulp , wherein the ratio of parts by weight between the talcum powder, hydroxypropyl methylcellulose, and nano-scale silicon dioxide is 3: 1.1: 0.96; specifically, taking 30kg of talc, 11kg of hydroxypropyl methylcellulose , the nanoscale silicon dioxide of 9.6kg is mixed and obtained; (2) preheating tablet: the tablet to be coated is placed in the coating equipment, such as Figure 1-7 As shown, the coating equipment includes an operation room 1, a spray gun 4, a jetting device 2, a feeding device 3 and a recovery device 5; The outer sleeve 21, the air-jet channel provided in the sleeve, the injection member 23 connected with the air-jet channel, and the blower 24, a heating element 25 is arranged between the blower 24 and the sleeve 21, and the heating elem...

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Abstract

The invention discloses a process based on the coating processing of medical tablets. (1) manufacturing a paddle: mixing talc, hydroxypropyl methylcellulose and nano-scale silicon dioxide to prepare a paddle; (2) preheating Tablets: Place the tablets in the coating equipment, spray hot air into the coating equipment through the jet device at the bottom of the coating equipment, and heat the inside of the coating equipment to heat the tablets; (3) Coating. Hydroxypropyl methylcellulose and nano-scale silicon dioxide are added to the coated paddle of the present invention, which not only makes the coating have good moisture-proof, anti-oxidation and anti-corrosion properties, but also effectively keeps the tablets from being oxidized, dampened and deteriorated. , which greatly improves the stability of the tablet; it can also slow down the speed of the outward release of the tablet's medicinal properties, so as to avoid stomach discomfort for the user.

Description

technical field [0001] The invention belongs to the technical field of feed additives, in particular to a process based on the coating processing of medical tablets. Background technique [0002] In the pharmaceutical industry, a layer of coating is generally applied to the outer surface of the tablet. This layer of coating can protect the tablet, prevent the tablet chip from oxidative deterioration, moisture or volatilization, and also conceal the unpleasant taste of the tablet when taking the tablet. Identify and mitigate the effects of dissolution in the human gastrointestinal tract. [0003] However, the existing coating is usually made of talc powder, and the obtained coating has poor moisture-proof and anti-oxidation effects, and it is difficult to achieve good moisture-proof and anti-deterioration effects after the tablet is coated. In addition, the existing coating process is usually to dry the tablet after all the coatings are completely coated, which takes a long ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J3/00
CPCA61J3/005Y02P70/10
Inventor 陈晓盛
Owner BEIJING TONGRENTANG XINGAN HEALTH TECH CO LTD
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