Preparation for resisting helicobacter pylori and relieving gingivitis and application thereof

Abstract

A preparation for resisting helicobacter pylori and relieving gingivitis is characterized by being prepared from the following components in percentage by mass: 50 to 80 percent of isoquinoline alkaloid, 1 to 10 percent of lactic acid bacteria (greater than or equal to 1011 cells / g) and 10 to 40 percent of biological polysaccharide. According to the invention, the helicobacter pylori inhibitor andthe anti-helicobacter pylori adhesive are combined for use, so that on one hand, the activity of oral harmful flora such as helicobacter pylori, porphyromonas gingivalis and fusobacterium nucleatum is inhibited through isoquinoline alkaloid, the plaque index is effectively reduced, and symptoms caused by gingivitis such as gingival bleeding and swelling and pain are relieved; on the other hand, adhesion of harmful bacteria is inhibited through direct interaction of lactic acid bacteria, biological polysaccharide and the harmful bacteria such as helicobacter pylori or blocking of available sites in a receptor, and secondary adhesion and field planting of the harmful bacteria such as helicobacter pylori in the oral cavity are prevented. The two synergistically act, so that the side effect of the bacteriostatic agent on beneficial bacteria is reduced.

Description

technical field [0001] The invention belongs to the technical field of oral care, and in particular relates to a preparation for resisting Helicobacter pylori and alleviating gingivitis and its application. Background technique [0002] Helicobacter pylori is a microaerophilic gram-negative bacterium that constitutes a common causative agent of chronic gastritis, peptic ulcer, mucosa-associated lymphoid tissue lymphoma, and gastric cancer, and the stomach is widely believed to be the primary growth site of H. pylori environment. With the deepening of research, Helicobacter pylori has also been detected in human oral dental plaque, saliva, mucosa of the back of the tongue, buccal mucosa, and palate mucosa, and it has been found that periodontal disease and oral mucosal disease are also related to Helicobacter pylori. [0003] Helicobacter pylori is an opportunistic pathogenic bacterium, which is commonly found in the oral cavity of healthy people and gastritis patients, and ...

AI Technical Summary

Problems solved by technology

These studies all focus on the direct bactericidal and bacteriostatic effects of active ingredients, but the uninhibited or newly entered oral cavity can still colonize the oral cavity, and there are few studies on anti-H. A product that effectively inhibits oral Helicobacter pylori and reduces the colonization of Helicobacter pylori in the oral environment, which is of great significance for the prevention and treatment of Helicobacter pylori infection

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