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Refreshing and moistening oral spray acting on sicca syndrome and preparation method thereof

A technology for oral spray and Sjogren's syndrome, applied in the field of moisturizing oral spray for Sjogren's syndrome and its preparation, can solve problems such as affecting the quality of life of patients, and achieve increasing local action time and effective dose, increasing action time, The effect of promoting saliva secretion

Inactive Publication Date: 2020-10-30
王海瑜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, 70%-80% of patients complain of dry mouth. In severe cases, due to the stickiness of oral mucosa, teeth and tongue, they need to drink water frequently when speaking, and need water assistance when swallowing dry food. Sometimes they need to get up at night to drink water, which seriously affects the The quality of life of patients. At present, the product research of traditional Chinese medicine spray in the treatment of dry mouth symptoms of Sjogren's syndrome is still blank. Therefore, there is a large market space and clinical demand for the research and development of such drugs

Method used

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  • Refreshing and moistening oral spray acting on sicca syndrome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The clearing and moistening mouth spray acting on Sjögren's syndrome comprises the following composition by weight: 30g of ebony plum, 6g of licorice, 15g of raw land, and 10g of green fruit.

[0021] The preparation method of the Qingrun oral spray acting on Sjögren's syndrome comprises the following steps:

[0022] Step 1, selection of raw materials: Purchasing high-quality ebony plums, licorice, raw land, and green fruits from the regular market, and weighing each component with an electronic scale according to the required amount of each component, and set aside;

[0023] Step 2, pulverizing: pulverize the ebony, licorice, rehmannia, and green fruit weighed in step 1 by a pulverizer to 20-50 mesh, and take out the pulverized raw materials for later use;

[0024] Step 3, base liquid preparation, put the crushed raw materials in step 2 into a container, pour warm water for soaking, the water temperature is 35°C, and the soaking time is 60 minutes. After soaking, repea...

Embodiment 2

[0030] The clearing and moistening mouth spray acting on Sjögren's syndrome comprises the following composition by weight ratio: 40g of ebony plum, 9g of licorice, 20g of raw land, and 15g of green fruit.

[0031] The preparation method of the Qingrun oral spray acting on Sjögren's syndrome comprises the following steps:

[0032] Step 1, selection of raw materials: Purchasing high-quality ebony plums, licorice, raw land, and green fruits from the regular market, and weighing each component with an electronic scale according to the required amount of each component, and set aside;

[0033] Step 2, pulverizing: pulverize the ebony, licorice, rehmannia, and green fruit weighed in step 1 by a pulverizer to 20-50 mesh, and take out the pulverized raw materials for later use;

[0034] Step 3, base liquid preparation, put the crushed raw materials in step 2 into a container, pour warm water for soaking, the water temperature is 35°C, and the soaking time is 60 minutes. After soaking,...

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Abstract

The invention discloses a refreshing and moistening oral spray acting on sicca syndrome and a preparation method of the refreshing and moistening oral spray. The refreshing and moistening oral spray is prepared from the following components in parts by weight: 30-40 g of smoked plums, 6-9 g of liquorice roots, 15-20 g of radix rehmanniae and 10-15 g of Chinese olives, the smoked plums serve as themain materials, the Chinese olives, the radix rehmanniae and the liquorice roots are added, the smoked plums and the liquorice roots are combined in the formula to nourish the yin with sour and sweet, and the Chinese olives, the radix rehmanniae have the effects for clearing away heat, nourishing yin and promoting fluid. The spray can directly act on secretory glands of the oral cavity, the localaction time and effective dose are increased, saliva secretion is promoted, and the compatibility of dark plum and liquorice roots has the effect of promoting proliferation of injured submandibular gland cells.

Description

technical field [0001] The invention relates to the field of spray-related products, in particular to a refreshing mouth spray for Sjögren's syndrome and a preparation method thereof. Background technique [0002] At present, the pathogenesis is not very clear. It is a disease with high incidence and can affect all age groups. The prevalence rate in my country is 0.29%-0.77%, and the prevalence rate in the elderly population is 3%-4%. The disease is more common in women, with a male to female ratio of 1:9-1:20. The age of onset is mostly 40-50 years old, and it can also be seen in children. As one of the diagnostic criteria of SS, xerostomia is the main symptom that troubles patients. Clinically, 70%-80% of patients complain of dry mouth. In severe cases, due to the stickiness of oral mucosa, teeth and tongue, they need to drink water frequently when speaking, and need water assistance when swallowing dry food. Sometimes they need to get up at night to drink water, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/12A61P1/02
CPCA61K9/006A61K36/32A61K36/484A61K36/736A61K36/804A61K2236/331A61P1/02A61K2300/00
Inventor 王海瑜侯秀娟康天伦柏志义白雪娇席雅婧
Owner 王海瑜
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