Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Anti-hair loss repair composition and application

A composition and a hair loss prevention technology, applied in the field of regenerative medicine, can solve the problems of damaged hair follicle soil, osmotic pressure imbalance of scalp tissue, obvious pain, etc., and achieve the advantages of promoting development and proliferation, treating hair loss well, and improving the effect of preventing hair loss. Effect

Active Publication Date: 2020-10-30
诺赛联合(北京)生物医学科技有限公司
View PDF6 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1. Use botulinum toxin: botulinum toxin blocks the transmission of nerve signals, making the scalp tissue in a relaxed state, which is conducive to the growth of hair; but long-term and repeated use will cause the thinning of the scalp tissue and damage the soil of the hair follicle;
[0007] 2. Using hyaluronic acid: Supplementing water and corresponding nutrients can promote hair growth, but repeated use will cause an imbalance of osmotic pressure in the scalp tissue (hypoosmotic);
[0008] 3. Hair transplantation: The operation process is cumbersome and painful, and the cost is relatively high, which cannot solve the problem of survival rate after hair follicle transplantation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Anti-hair loss repair composition and application
  • Anti-hair loss repair composition and application
  • Anti-hair loss repair composition and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] A kind of anti-hair loss repairing composition, described anti-hair loss repairing composition comprises:

[0078] will be 5×10 6 Hair follicle progenitor cells were resuspended with 10mL human adipose-derived mesenchymal stem cell lysate, and 0.4mL mesenchymal stem cell factor and 0.4mL platelet-rich fibrin were added;

[0079] Human adipose-derived mesenchymal stem cell lysate is prepared by a method comprising the following steps:

[0080] will be 5×10 7 Human adipose-derived mesenchymal stem cells were digested, dissolved in 10mL of normal saline, frozen in liquid nitrogen, and quickly thawed at 37°C. After 4 freeze-thaw cycles, human adipose-derived mesenchymal stem cells were broken, and the product was obtained.

Embodiment 2

[0082] A kind of anti-hair loss repairing composition, described anti-hair loss repairing composition comprises:

[0083] Will 1×10 6 Hair follicle progenitor cells were resuspended with 10mL human adipose-derived mesenchymal stem cell lysate, and 0.3mL mesenchymal stem cell factor and 0.3mL platelet-rich fibrin were added;

[0084] Human adipose-derived mesenchymal stem cell lysate is prepared by a method comprising the following steps:

[0085] Will 4×10 7 Human adipose-derived mesenchymal stem cells were digested, dissolved in 10mL of normal saline, frozen in liquid nitrogen, and quickly thawed at 37°C. After 4 freeze-thaw cycles, human adipose-derived mesenchymal stem cells were broken, and the product was obtained.

Embodiment 3

[0087] A kind of anti-hair loss repairing composition, described anti-hair loss repairing composition comprises:

[0088] Will 1×10 7 Hair follicle progenitor cells were resuspended with 10mL human adipose-derived mesenchymal stem cell lysate, and 0.5mL mesenchymal stem cell factor and 0.5mL platelet-rich fibrin were added;

[0089] Human adipose-derived mesenchymal stem cell lysate is prepared by a method comprising the following steps:

[0090] will be 6×10 7 Human adipose-derived mesenchymal stem cells were digested, dissolved in 10mL of normal saline, and crushed by a cell disruptor.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The embodiment of the invention relates to regenerative medicine, in particular to an anti-hair loss repair composition and an application. The anti-hair loss repair composition provided by the embodiment of the invention comprises hair follicle progenitor cells, mesenchymal stem cell factors, a mesenchymal stem cell lysate and platelet-rich fibrin, wherein every 10 mL of mesenchymal stem cell lysis buffer is mixed with (1-10)*10 <6> hair follicle progenitor cells, 0.2-0.6 mL of a mesenchymal stem cell factor and 0.2-0.6 mL of platelet-rich fibrin, and the mesenchymal stem cell lysate is prepared by a method comprising the following steps: digesting (1-10)*10<7> mesenchymal stem cells, dissolving the digested mesenchymal stem cells in 10mL of normal saline, and carrying out freeze thawingor mechanical crushing to obtain the mesenchymal stem cell lysate. The anti-hair loss repair composition provided by the invention can fundamentally solve the problem of hair follicles, enables the hair follicles to recover functions again, and has a good effect of treating alopecia.

Description

technical field [0001] The invention relates to regenerative medicine, in particular to an anti-hair loss repairing composition and its application. Background technique [0002] According to the World Health Organization, 1 out of every 5 adult males suffers from hair loss, while 1 out of 20 women suffers from hair loss. [0003] The problem of hair loss in our country tends to be younger. Now the post-80s and post-90s have gradually become the main force of hair loss. The proportion of hair loss in this group has exceeded 35%. Baldness caused by overwork and obesity has troubled many people. [0004] According to the "China Hair Loss Population Survey", there are about 200 million hair loss people in my country, and 90% of them will not get better if they die. The number of men with hair loss is about 130 million, and the male hair loss rate in my country is nearly 20%. Among them, men aged 20-40 are the main force of hair loss. [0005] There are three main methods on ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/36A61P17/14C12N5/071A61K35/28A61K35/16
CPCA61K35/36A61K35/28A61K35/16A61P17/14C12N5/0628C12N2509/00C12N2509/10A61K2300/00
Inventor 亓爱杰李少波马宏磊亓爱磊
Owner 诺赛联合(北京)生物医学科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com