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Use method and application of iron supplementing agent iron dextran

A technology of iron dextran and iron supplement, applied in the field of animal husbandry, can solve the problems of how the piglet body is damaged, the increase of piglet diarrhea rate, and no related research, so as to improve the production performance of piglets, reduce the diarrhea rate of piglets, increase the The effect of breeding benefits

Inactive Publication Date: 2020-10-09
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when a large dose of iron is injected into the piglets, it will cause stress to the piglets, and the diarrhea rate of the piglets will increase for a short time, and severe cases may even lead to death
However, there is no relevant research on the mechanism of how the piglet body is damaged

Method used

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  • Use method and application of iron supplementing agent iron dextran
  • Use method and application of iron supplementing agent iron dextran
  • Use method and application of iron supplementing agent iron dextran

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 A method of using iron supplement iron dextran

[0023] Eight litters of newborn Du×big×long piglets of the same parity and similar body weight were selected and randomly divided into two iron supplementation groups (Fe 40+40) and one iron supplementation group (Fe 150), with 4 replicates in each group. Repeat for 7-10 heads. Iron dextran injection was selected as iron supplement (iron dextran for veterinary use, produced by Jiangxi Chuangxin Pharmaceutical Group Co., Ltd., 10 ml×10 sticks, 10 ml as iron: 1 g). The control group (Con) consisted of 1 head / litter in the iron supplementation group twice and 2 heads / litter in the iron supplementation group once. A total of 12 animals were marked with ear tags. A total of 81 piglets were tested. After the piglets were born, the control group did not receive iron supplementation. Based on the conversion of piglets weighing 1.5 kg on the 3rd day and 3.75 kg on the 14th day, 0.4 ml (40 mg iron) iron dextran injectio...

Embodiment 2

[0024] Example 2 Application of an iron supplement iron dextran

[0025] Analysis of results

[0026] After piglets were supplemented with iron according to the method in Example 1, the body weight of piglets in each group was recorded every 5 days, the daily gain was calculated, and the diarrhea rate of piglets was recorded. Diarrhea rate=diarrhea piglet head time / (test piglet head number × test days) × 100%. The weight of piglets in the iron supplementation group twice was significantly higher than that in the control group and the iron supplementation group once, which was 0.85 kg higher than that in the iron supplementation group once ( figure 1 A). The diarrhea rate of piglets in the iron supplementation group twice was 4.9%, which was significantly lower than the 9.4% in the iron supplementation group once ( figure 1 B). The daily gain of piglets in the iron supplementation group twice was significantly higher than that in the control group and the iron supplementati...

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Abstract

The invention discloses a use method and application of an iron supplementing agent iron dextran. The method is characterized by supplementing iron twice, respectively using 0.6 ml (60 mg of iron) and1.5 ml (150 mg of iron) of iron dextran injection (10 ml * 10 iron dextran agents for livestock, 10 ml: 1 g based on iron, and concentration of iron dextran is 0.1 g / ml)on the third day and the fourteenth day of piglet birth, and performing neck intramuscular injection on the piglets to supplement iron. The application of twice iron supplementation is used for improving the production performanceof the piglets and reducing the diarrhea rate of the piglets; the invention is used for effectively preventing iron-deficiency anemia of piglets and improving the iron absorption and utilization efficiency of piglets and improving body iron storage. The invention is used for promoting healthy development of intestinal tracts of piglets, defining the mechanism of iron supplementation on oxidativedamage and cell autophagy of the piglets, so that the bodies of the piglets are prevented from oxidative damage and cell autophagy disorder, and the culture benefit is increased.

Description

technical field [0001] The invention belongs to the technical field of animal husbandry, and in particular relates to a method for using iron supplementation iron dextran to improve the growth performance of piglets. Background technique [0002] Iron is one of the most important trace elements among many nutrients in the body. It participates in the composition of various cellular enzymes and completes important biochemical processes in the body, including decomposing nutrients to enable the body to obtain energy, decomposing metabolic waste, detoxifying and sterilizing, etc. Iron can synthesize myoglobin and hemoglobin, and participate in the transport of oxygen and various nutrients needed by the human body. It can also maintain the normal bactericidal function of immune cells such as T cells and neutrophils, and also plays an important role in the body's immune system. When the body is deficient in iron, enzyme activity decreases, red blood cell transport ability also d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K33/26A61K31/721A61P7/06A61D7/00
CPCA61D7/00A61K9/0019A61K9/08A61K31/721A61K33/26A61P7/06
Inventor 杜华华熊晴晴陈小云赵婧汪以真
Owner ZHEJIANG UNIV
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